Benutzerspezifische Werkzeuge

Developement of middle ear implants

Developement of middle ear implants

The lab can reflect upon a long history of research on middle ear reconstruction. Various ossicular replacement prostheses have been tested and developed.  Flexible prostheses with an integrated microjoint are the current challenge in research ( Flexible ossicular replacement prosthesis ).

Advanced manufacturing technologies in 3D printing (like Electrospinning, Fused Deposition Modeling) allow for new methods/therapies in tympanic membrane reconstruction a highly topical field of research.


  • Stoppe, T., Bornitz, M., Lasurashvili, N., Sauer, K., Zahnert, T., Zaoui, K., Beleites, T., 2018. Function, Applicability, and Properties of a Novel Flexible Total Ossicular Replacement Prosthesis With a Silicone Coated Ball and Socket Joint . Otology & Neurotology 39, 739–747.
  • Stoppe, T., Bornitz, M., Lasurashvili, N., Sauer, K., Zahnert, T., Beleites, T., 2017. Middle ear reconstruction with a flexible prosthesis . Current Directions in Biomedical Engineering 3, 143–146.

  • Neudert, M., Bornitz, M., Lasurashvili, N., Schmidt, U., Beleites, T., Zahnert, T., 2016. Impact of Prosthesis Length on Tympanic Membrane’s and Annular Ligament’s Stiffness and the Resulting Middle Ear Sound Transmission . Otol Neurotol 37, e369–e376.
  • Arechvo, I., Bornitz, M., Lasurashvili, N., Zahnert, T., Beleites, T., 2012. New total ossicular replacement prostheses with a resilient joint: experimental data from human temporal bones . Otol Neurotol 33, 60–66.

  • Arechvo, I., Zahnert, T., Bornitz, M., Neudert, M., Lasurashvili, N., Simkunaite-Rizgeliene, R., Beleites, T., 2012. The ostrich middle ear for developing an ideal ossicular replacement prosthesis . Eur Arch Otorhinolaryngol 270, 37–44.

  • Beleites, T., Bornitz, M., Offergeld, C., Neudert, M., Hüttenbrink, K.-B., Zahnert, T., 2007. Experimental investigations on middle ear prostheses with an integrated micro joint . Laryngorhinootologie 86, 649–654.

  • Hüttenbrink, K.-B., Zahnert, T., Wüstenberg, E.G., Hofmann, G., 2004. Titanium clip prosthesis. Otol Neurotol 25, 436–442.