Publications
2023
Ragavan, V.N., Nair, P.C., Jarzebska, N., Angom, R. S., Ruta, L., Bianconi, E., Grottelli, S., Tararova, N.D., Ryazanskiy, D., Lentz, S.R., Tommasi, S., Martens-Lobenhoffer, J., Suzuki-Yamamoto, T., Kimoto, M., Rubets, E., Chau, S., Chen, Y., Hu, X., Bernhardt, N., Spieth, P.M., Weiss, N., Bornstein, S.R., Mukhopadhyay, D., Bode-Böger, S.M., Maas, R., Wang, Y., Macchiarulo, A., Mangoni, A.A., Cellini, B., Rodionov, R.N. (2023). A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase. Nature communications. https://doi.org/10.1038/s41467-023-38467-9
Edemann-Callesen, H., Bernhardt, N., Hlusicka, E.B., Hintz, F., Habelt, B., Winter, R., Neubert, I., Pelz, M., Filla, A., Soto-Montenegro, M.L., Winter, C., Hadar, R. (2023). Supplement Treatment with NAC and Omega-3 Polyunsaturated Fatty Acids during Pregnancy Partially Prevents Schizophrenia-Related Outcomes in the Poly I:C Rat Model. Antioxidants. https://doi.org/10.3390/antiox12051068
Kozlova, A.A., Rubets, E., Vareltzoglou, M.R., Jarzebska, N., Ragavan, V.N., Chen, Y., Martens-Lobenhoffer, J., Bode-Böger, S.M., Gainetdinov, R.R., Rodionov, R.N., & Bernhardt, N. (2023). Knock-out of the critical nitric oxide synthase regulator DDAH1 in mice impacts amphetamine sensitivity and dopamine metabolism. Journal of Neural Transmission. https://doi.org/10.1007/s00702-023-02597-7
2022
Kozlova, A.A., Vaganova, A.N., Rodionov, R.N., Gainetdinov, R.R., Bernhardt, N. (2022). Assessment of DDAH1 and DDAH2 Contributions to Psychiatric Disorders via In Silico Methods. Inernational Journal of Molecular Sciences. https://doi.org/10.3390/ijms231911902
Edemann-Callesen, H., Glienke, M., Akinola, E. O., Lieser, M. K., Habelt, B., Hadar, R., Bernhardt, N., Winter, C. (2022). Former Training Relieves the Later Development of Behavioral Inflexibility in an Animal Model Overexpressing the Dopamine Transporter. Molecular Neurobiology. https://doi.org/10.1007/s12035-022-03029-5
Szegö, EM., Malz, L., Bernhardt, N., Rösen-Wolff, A., Falkenburger, BH., Luksch, H. (2022). Constitutively active STING causes neuroinflammation and degeneration of dopaminergic neurons in mice. bioRxiv. https://www.biorxiv.org/content/10.1101/2022.02.02.478854v2
Bernhardt, N*., Memic, F*., Velica, A., Tran, M. A., Vieillard, J., Chersa, T., Andersson, L., Whelan, P. J., Boije, H., & Kullander, K. (2022). Hop Mice Display Synchronous Hindlimb Locomotion and a Ventrally Fused Lumbar Spinal Cord Caused by a Point Mutation in Ttc26. eNeuro, 9 (2). https://doi.org/10.1523/ENEURO.0518-21.2022
2021
Habelt, B., Wirth, C., Afanasenkau, D., Mihaylova, L., Winter, C., Arvaneh, M., Minev, I.R., and Bernhardt, N. (2021). A multimodal neuroprosthetic interface to record, modulate and classify electrophysiological correlates of cognitive function. Frontiers in Bioengineering and Biotechnology 9,1061. https://doi.org/10.3389/fbioe.2021.770274
Kozlova, A.A., Ragavan, V.N., Jarzebska, N., Lukianova, I., Anastasia, B., Rubets, E., Suzuki-Yamamoto, Kimoto, M., Mangoni, A.A., Gainetdinov, R.R., Weiss, N., Bauer, M., Markov, A., Rodionov, R.N., Bernhardt, N., (2021). Divergent dimethylarginine dimethylaminohydrolase isoenzyme expression in the central nervous system. Cellular and Molecular Neurobiology https://doi.org/10.1007/s10571-021-01101-7
Petrasek, T., Vojtechova, I., Klovrza, O., Tuckova, K., Vejmola, C., Rak, J., Sulakova, A., Kaping, D., Bernhardt, N., Vries, P. de, Otahal, J., Waltereit, R., (2021). mTOR inhibitor improves autistic-like behaviors related to Tsc2 haploinsufficiency but not following developmental status epilepticus. Journal Neurodevelopmental Disorders 13, 14. https://doi.org/10.1186/s11689-021-09357-2
2020
Winter, R., Akinola, B., Barroeta-Hlusicka, E., Meister, S., Pietzsch, J., Winter, C., & Bernhardt, N. (2020). Comparison of manual and automated ventricle segmentation in the maternal immune stimulation rat model of schizophrenia. bioRxiv, 2020.06.10.144022. https://doi.org/10.1101/2020.06.10.144022
Bernhardt, N., Petzold, J., Groß, C., Scheck, A., Pooseh, S., Mayer-Pelinski, R., Zimmermann, U. S., Smolka, M. N., & Pilhatsch, M. (2020). Neurocognitive Dysfunctions and Their Therapeutic Modulation in Patients with Methamphetamine Dependence: A Pilot Study. Frontiers in Psychiatry, 11, 581. https://doi.org/10.3389/fpsyt.2020.00581
Bernardoni, F., Bernhardt, N., Pooseh, S., King, J. A., Geisler, D., Ritschel, F., Boehm, I., Seidel, M., Roessner, V., Smolka, M. N., & Ehrlich, S. (2020). Metabolic state and value-based decision-making in acute and recovered female patients with anorexia nervosa. Journal of Psychiatry & Neuroscience : JPN, 45(4), 253–261. https://doi.org/10.1503/jpn.190031
Habelt, B., Arvaneh, M., Bernhardt, N., & Minev, I. (2020). Biomarkers and neuromodulation techniques in substance use disorders. Bioelectronic Medicine, 6, 4. https://doi.org/10.1186/s42234-020-0040-0
Hadar, R., Winter, R., Edemann-Callesen, H., Wieske, F., Habelt, B., Khadka, N., Felgel-Farnholz, V., Barroeta-Hlusicka, E., Reis, J., Tatarau, C. A., Funke, K., Fritsch, B., Bernhardt, N., Bikson, M., Nitsche, M. A., & Winter, C. (2020). Prevention of schizophrenia deficits via non-invasive adolescent frontal cortex stimulation in rats. Molecular Psychiatry, 25(4), 896–905. https://doi.org/10.1038/s41380-019-0356-x
Meyerolbersleben, L., Winter, C., & Bernhardt, N. (2020). Dissociation of wanting and liking in the sucrose preference test in dopamine transporter overexpressing rats. Behavioural Brain Research, 378, 112244. https://doi.org/10.1016/j.bbr.2019.112244
Sommer, C., Birkenstock, J., Garbusow, M., Obst, E., Schad, D. J., Bernhardt, N., Huys, Q. M., Wurst, F. M., Weinmann, W., Heinz, A., Smolka, M. N., & Zimmermann, U. S. (2020). Dysfunctional approach behavior triggered by alcohol-unrelated Pavlovian cues predicts long-term relapse in alcohol dependence. Addiction Biology, 25(1), e12703. https://doi.org/10.1111/adb.12703
Obst, E., Bernhardt, N., Gan, G., Plawecki, M. H., O’Connor, S., Smolka, M. N., & Zimmermann, U. S. (2020). Sensation seeking, impulsivity, and aggression moderate sex effects on adolescent laboratory binging. Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors. https://doi.org/10.1037/adb0000651
Petzold, J., Weber, B., Bassett, T. R., Bauer, M., Bernhardt, N., Groß, C., Hasler, H., Schützwohl, M., & Pilhatsch, M. (2020). Effectiveness of the First German-Language Group Psychotherapy Manual to Accompany Short-Term Treatment in Methamphetamine Dependence. Frontiers in Psychiatry, 11, 130. https://doi.org/10.3389/fpsyt.2020.00130
2019
Bernhardt, N., Obst, E., Nebe, S., Pooseh, S., Wurst, F. M., Weinmann, W., Smolka, M. N., & Zimmermann, U. S. (2019). Acute alcohol effects on impulsive choice in adolescents. Journal of Psychopharmacology (Oxford, England), 33(3), 316–325. https://doi.org/10.1177/0269881118822063
Schad, D. J., Garbusow, M., Friedel, E., Sommer, C., Sebold, M., Hägele, C., Bernhardt, N., Nebe, S., Kuitunen-Paul, S., Liu, S., Eichmann, U., Beck, A., Wittchen, H.-U., Walter, H., Sterzer, P., Zimmermann, U. S., Smolka, M. N., Schlagenhauf, F., Huys, Q. J. M., … Rapp, M. A. (2019). Neural correlates of instrumental responding in the context of alcohol-related cues index disorder severity and relapse risk. European Archives of Psychiatry and Clinical Neuroscience, 269(3), 295–308. https://doi.org/10.1007/s00406-017-0860-4
2018
Bernhardt, N., Lieser, M. K., Hlusicka, E.-B., Habelt, B., Wieske, F., Edemann-Callesen, H., Garthe, A., & Winter, C. (2018). Learning deficits in rats overexpressing the dopamine transporter. Scientific Reports, 8(1), 14173. https://doi.org/10.1038/s41598-018-32608-7
Edemann-Callesen, H., Habelt, B., Wieske, F., Jackson, M., Khadka, N., Mattei, D., Bernhardt, N., Heinz, A., Liebetanz, D., Bikson, M., Padberg, F., Hadar, R., Nitsche, M. A., & Winter, C. (2018). Non-invasive modulation reduces repetitive behavior in a rat model through the sensorimotor cortico-striatal circuit. Translational Psychiatry, 8(1), 11. https://doi.org/10.1038/s41398-017-0059-5
Nebe, S., Kroemer, N. B., Schad, D. J., Bernhardt, N., Sebold, M., Müller, D. K., Scholl, L., Kuitunen-Paul, S., Heinz, A., Rapp, M. A., Huys, Q. J. M., & Smolka, M. N. (2018). No association of goal-directed and habitual control with alcohol consumption in young adults. Addiction Biology, 23(1), 379–393. https://doi.org/10.1111/adb.12490
Pooseh, S., Bernhardt, N., Guevara, A., Huys, Q. J. M., & Smolka, M. N. (2018). Value-based decision-making battery: A Bayesian adaptive approach to assess impulsive and risky behavior. Behavior Research Methods, 50(1), 236–249. https://doi.org/10.3758/s13428-017-0866-x
2017
Bernhardt, N., Nebe, S., Pooseh, S., Sebold, M., Sommer, C., Birkenstock, J., Zimmermann, U. S., Heinz, A., & Smolka, M. N. (2017). Impulsive Decision Making in Young Adult Social Drinkers and Detoxified Alcohol-Dependent Patients: A Cross-Sectional and Longitudinal Study. Alcoholism, Clinical and Experimental Research, 41(10), 1794–1807. https://doi.org/10.1111/acer.13481
Jünger, E., Javadi, A.-H., Wiers, C. E., Sommer, C., Garbusow, M., Bernhardt, N., Kuitunen-Paul, S., Smolka, M. N., & Zimmermann, U. S. (2017). Acute alcohol effects on explicit and implicit motivation to drink alcohol in socially drinking adolescents. Journal of Psychopharmacology (Oxford, England), 31(7), 893–905. https://doi.org/10.1177/0269881117691454
Sommer, C., Garbusow, M., Jünger, E., Pooseh, S., Bernhardt, N., Birkenstock, J., Schad, D. J., Jabs, B., Glöckler, T., Huys, Q. M., Heinz, A., Smolka, M. N., & Zimmermann, U. S. (2017). Strong seduction: Impulsivity and the impact of contextual cues on instrumental behavior in alcohol dependence. Translational Psychiatry, 7(8), e1183. https://doi.org/10.1038/tp.2017.158
Bernhardt, N., Lieser, M., Edemann Callesen, H., Garthe, A., & Winter, C. (2017). Learning deficits and hippocampal neurogenesis in rats overexpressing the dopamine transporter. European Neuropsychopharmacology, 27, S764–S765. https://doi.org/10.1016/S0924-977X(17)31397-4
< 2016
Garbusow, M., Schad, D. J., Sebold, M., Friedel, E., Bernhardt, N., Koch, S. P., Steinacher, B., Kathmann, N., Geurts, D. E. M., Sommer, C., Müller, D. K., Nebe, S., Paul, S., Wittchen, H.-U., Zimmermann, U. S., Walter, H., Smolka, M. N., Sterzer, P., Rapp, M. A., … Heinz, A. (2016). Pavlovian-to-instrumental transfer effects in the nucleus accumbens relate to relapse in alcohol dependence. Addiction Biology, 21(3), 719–731. https://doi.org/10.1111/adb.12243
Sommer, C., Schad, D., Bernhardt, N., Sebold, M., Garbusow, M., Jünger, E., Jabs, B., Glöckler, T., & Zimmermann, U. (2015). Impulsivität als Verstärker von Kontextreizen – Pavlovian-to-Instrumental-Transfer bei Patienten mit Alkoholabhängigkeit. Suchttherapie, 16(S 1), S_27_01. https://doi.org/10.1055/s-0035-1557598
Schad, D. J., Jünger, E., Sebold, M., Garbusow, M., Bernhardt, N., Javadi, A.-H., Zimmermann, U. S., Smolka, M. N., Heinz, A., Rapp, M. A., & Huys, Q. J. M. (2014). Processing speed enhances model-based over model-free reinforcement learning in the presence of high working memory functioning. Frontiers in Psychology, 5, 1450. https://doi.org/10.3389/fpsyg.2014.01450
Bernhardt, N. R., Memic, F., & Kullander, K. (2013). Genetic analysis of left-right coordination of locomotion. Frontiers in Bioscience (Landmark Edition), 18, 21–35. https://doi.org/10.2741/4085
Garbusow, M., Sebold, M., Bernhardt, N., Nebe, S., Hägele, C., Friedel, E., Beck, A., Keller, J., Smolka, M. N., & Heinz, A. (2013). Risikofaktoren für die Entstehung einer Alkoholabhängigkeit – Lernmechanismen und deren neuronale Korrelate. Suchttherapie, 14(S 1), S_49_3. https://doi.org/10.1055/s-0033-1351593
Bernhardt, N., Memic, F., Gezelius, H., Thiebes, A.-L., Vallstedt, A., & Kullander, K. (2012). DCC mediated axon guidance of spinal interneurons is essential for normal locomotor central pattern generator function. Developmental Biology, 366(2), 279–289. https://doi.org/10.1016/j.ydbio.2012.03.017
Lundell, I., Bernhardt, N., Johnsson, A.-K., & Larhammar, D. (2011). Internalization studies of chimeric neuropeptide Y receptors Y1 and Y2 suggest complex interactions between cytoplasmic domains. Regulatory Peptides, 168(1–3), 50–58. https://doi.org/10.1016/j.regpep.2011.03.004
Enjin, A., Rabe, N., Nakanishi, S. T., Vallstedt, A., Gezelius, H., Memic, F., Lind, M., Hjalt, T., Tourtellotte, W. G., Bruder, C., Eichele, G., Whelan, P. J., & Kullander, K. (2010). Identification of novel spinal cholinergic genetic subtypes disclose Chodl and Pitx2 as markers for fast motor neurons and partition cells. The Journal of Comparative Neurology, 518(12), 2284–2304. https://doi.org/10.1002/cne.22332
Rabe, N., Gezelius, H., Vallstedt, A., Memic, F., & Kullander, K. (2009). Netrin-1-dependent spinal interneuron subtypes are required for the formation of left-right alternating locomotor circuitry. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, 29(50), 15642–15649. https://doi.org/10.1523/JNEUROSCI.5096-09.2009
Lagerström, M. C., Rabe, N., Haitina, T., Kalnina, I., Hellström, A. R., Klovins, J., Kullander, K., & Schiöth, H. B. (2007). The evolutionary history and tissue mapping of GPR123: Specific CNS expression pattern predominantly in thalamic nuclei and regions containing large pyramidal cells. Journal of Neurochemistry, 100(4), 1129–1142. https://doi.org/10.1111/j.1471-4159.2006.04281.x
Wegmeyer, H., Egea, J., Rabe, N., Gezelius, H., Filosa, A., Enjin, A., Varoqueaux, F., Deininger, K., Schnütgen, F., Brose, N., Klein, R., Kullander, K., & Betz, A. (2007). EphA4-dependent axon guidance is mediated by the RacGAP alpha2-chimaerin. Neuron, 55(5), 756–767. https://doi.org/10.1016/j.neuron.2007.07.038
Merten, N., Lindner, D., Rabe, N., Römpler, H., Mörl, K., Schöneberg, T., & Beck-Sickinger, A. G. (2007). Receptor subtype-specific docking of Asp6.59 with C-terminal arginine residues in Y receptor ligands. The Journal of Biological Chemistry, 282(10), 7543–7551. https://doi.org/10.1074/jbc.M608902200