Benutzerspezifische Werkzeuge

Neurobiology of Psychiatric Disorders

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Research focus

Neuronal networks form the basal functional units of the nervous system and thus the ability to react to external stimuli and regulate internal body functions. Despite a high level of knowledge gained in recent decades, we have only just begun to understand the complex physiological functions of the brain and the pathological changes associated with neuropsychiatric diseases. Our primary goal is to describe disease-specific pathomechanisms with regard to a longitudinal developmental perspective. We do this predominantly via studies in valid animal models of psychiatric disorders with genetic, environmental or multifactorial etiology, which allow an in depth investigation of neurobiological correlates of behavioral abnormalities at all levels of brain integrity. Our long-term aim is to establish 1) new approaches to interfere with symptom manifestation and 2) preventive treatment strategies with translational value.

Approaches to study neuropsychiatric disorders in our labApproaches to study neuropsychiatric disorders in our lab

We are closely connected with Mental Health Dresden-Leipzig,  a regional research network, comprising the Technische Universität Dresden, the Universität Leipzig, and the Robert Koch Institute. Mental Health Dresden-Leipzig has particular strengths and expertise in clinical psychiatry, neuro- and cognitive psychology, basic and clinical neuroscience, epidemiology, environmental sociology, and public mental health. The infrastructure includes neuropsychiatric research facilities, a digital health centre, existing longitudinal cohort and population studies, regional networks of district hospitals, services and community organisations in Saxony, and international collaborations including the transCampus® network for Mental Health.

MD Thesis available

We are looking for a highly motivated student that would like to perform a preclinical-experimental study informing the potential of preventive brain stimulation techniques for psychiatric disorders. For the success of the project, affinity to Matlab, Python and/or R is recommendable. The student will have the chance to participate in regular meetings with our partner Lab at King`s College London in addition to an on-site visit through the existing TransCampus network to obtain knowledge on state-of-the-art MRI data processing. The student will also learn how to perform multifaceted data analysis and manuscript preparation for a scientific publication. The samples for the study are already available. Thus, this study's experimental part and data analysis can be completed in 12 months with one free semester. Financial supported is available. The doctoral thesis can be written in English or German. If you are interested please contact: nadine.bernhardt@tu-dresden.de

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