Benutzerspezifische Werkzeuge

Publications

  • Burdin D.V., Kolobov A.A., Demyanov A.V., Soshnev A.A., Brocker C., Samusik N., Brilloff S., Martens-Lobenhoffer J., Mieth M., Maas R., Bornstein S.R., Bode-Böger S.M., Gonzalez F., Weiss N., Rodionov R.N. Hepatic Nuclear Factor 4α (HNF4α) is the major regulator of alanine-glyoxylate aminotransferase 2 (AGXT2) expression – a novel link between diabetes and impaired metabolism of endogenous methylarginines. In revision in J Biol Chem. (2015)
  • Rodionov R.N., Martens-Lobenhoffer J., Brilloff S., Burdin D.V., Jarzebska N., Demyanov A.V., Hohenstein B., Weiss N., Bode-Böger S.M. Acetylation of asymmetric and symmetric dimethylarginine – an undercharacterized pathway of metabolism of endogenous methylarginines. Nephrol Dial Transplant. 2015 Nov 25. pii: gfv390.
  • Rodionov R.N., Jarzebska N., Weiss N., Lentz S.R., AGXT2: a promiscuous aminotransferase. Trends Pharmacol Sci. 2014 Nov;35(11):575-82.
  • Rodionov R.N., Martens-Lobenhoffer J., Brilloff S., Hohenstein B., Jarzebska N., Jabs N., Kittel A., Maas R., Weiss N., Bode-Böger S.M., Role of alanine:glyoxylate aminotransferase 2 in metabolism of asymmetric dimethylarginine in the settings of asymmetric dimethylarginine overload and bilateral nephrectomy. Nephrol Dial Transplant. 2014 Nov;29(11):2035-42.
  • Martens-Lobenhoffer J., Rodionov R.N., Bode-Böger S.M. Determination of asymmetric Nα-acetyl-dimethylarginine in humans: a phase II metabolite of asymmetric. Anal Biochem. 2014 May 1;452:25-30.
  • Lim S.K., Choi H., Park M.J., Kim D.I., Kim J.C., Kim G.Y., Jeong S.Y., Rodionov R.N., Han H.J., Yoon K.C., Park S.H. The ER stress-mediated decrease in DDAH1 expression is involved in formaldehyde-induced apoptosis in lung epithelial cells. Food Chem Toxicol. 2013 Oct 16
  • Deepa K., Rodionov R.N., Weiss N., Parani M. Transgenic Expression and Functional Characterization of Human Platelet Derived Growth Factor BB (hPDGF-BB) in Tobacco (Nicotiana tabacum L.). Appl Biochem Biotechnol. 2013 Aug 18
  • Kittel A., Maas R., König J., Mieth M., Weiss N., Jarzebska N., Hohenstein B., Martens-Lobenhoffer J., Bode-Böger S.M., Rodionov R.N., In vivo evidence that Agxt2 can regulate plasma levels of dimethylarginines in mice. Biochem Biophys Res Commun. 2013 Jan 4;430(1):84-9.
  • Martens-Lobenhoffer J., Rodionov R.N., Bode-Böger S.M., Probing AGXT2 enzyme activity in mouse tissue by applying stable isotope-labeled asymmetric dimethyl arginine as substrate. J Mass Spectrom. 2012; 47: 1594-1600.
  • Martens-Lobenhoffer J., Rodionov R.N., Drust A, Bode-Böger S.M., Detection and quantification of -keto--(NG,NG-dimethylguanidino)valeric acid (DMGV) in human plasma and urine: a metabolite of asymmetric dimethylarginine (ADMA) relevant for the nitric oxide homeostasis. Anal Biochem. 2011 Dec 15;419(2):234-40
  • Rodionov R.N., Murry D.J., Vaulman S.F., Stevens J.W., Lentz S.R. Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production. J Biol Chem. 2010 Feb 19;285(8):5385-91.
  • Rodionov R.N., Dayoub H., Lynch C.M., Wilson K.M., Stevens J.W., Murry D.J., Kimoto M., Arning E., Bottiglieri T., Cooke J.P., Baumbach G.L., Faraci F.M., Lentz S.R. Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia. Circ Res. 2010 Feb 19;106(3):551-8.
  • Rodionov R.N. and Lentz S.R. Many potential explanations for the homocysteine paradox. Arterioscler Thromb Vasc Biol. 2008 Oct; 28(10): e161.
  • Dayal S., Rodionov R.N., Arning E., Bottiglieri T., Kimoto M., Murry D.J., Cooke J.P., Faraci F.M., Lentz S.R. Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia. Am J Physiol Heart Circ Physiol. 2008 Aug;295(2):H816-25.
  • Rodionov R.N. and Lentz S.R. The Homocysteine Paradox. Arterioscler Thromb Vasc Biol. 2008 Jun;28(6):1031-3
  • Dayoub H., Rodionov R.N., Lynch C., Cooke J.P., Arning E., Bottiglieri T., Lentz S.R., Faraci F.M. Overexpression of dimethylarginine dimethylaminohydrolase inhibits asymmetric dimethylarginine-induced endothelial dysfunction in the cerebral circulation. Stroke. 2008 Jan;39(1):180-4.