Benutzerspezifische Werkzeuge

Post-doctoral position in bioinformatics/biology (f/m/x)

The National Center for Tumor Diseases (NCT) was founded by the University Clinic Carl Gustav Carus Dresden, the Medical Faculty of the TU Dresden, the Helmholtz-Zentrum Dresden-Rossendorf and the German Cancer Research Center (DKFZ). With its research sites in Dresden and Heidelberg, the NCT is the leading oncology center in Germany and plans to develop into a top center internationally that is committed to individualized, patient-side cancer medicine. The successful candidate will be employed through the TU Dresden and work at the University Clinic Dresden in the framework of an ERA PreMed Grant, where he/she will be part of a newly establish NCT junior group that is located in the Department of Pediatrics at the University Clinic Dresden (Leader: Prof. Dr. Julia Hauer). The research focus of our team is in oncology/immunology with a special interest in inherited predispositions to pediatric cancer with a particular attention on childhood leukemias.

Starting at July, 1st 2019 we would like to recruit a

Post-doctoral position in bioinformatics/biology (f/m/x)

This fulltime-position is limited to a 2 year period, with extension potential.

Since 2019 we have implemented a trio-sequencing study that collects next generation sequencing data of child-parent trios of children newly diagnosed with cancer at our hospital. The here offered position revolves around processing and analyzing this data and its comparison to other available in-house and external datasets. A pilot study, which has been ongoing in Düsseldorf, Germany, since 2016, has already shown the power and effectiveness of a trio-sequencing approach in regard to the identification of new cancer predisposing genes in childhood.

The goal of this study is to not only extend the knowledge of pediatric cancer predisposition, but also to systematically depict its involvement in childhood cancers by incorporating new approaches like digenic predisposition as well as child/adult comparisons. Functional validation of the results will be performed in the wet-lab, by a team of biologists that are specialized in elucidating the significance of variants of unknown significance (VUS) in-vitro and in-vivo.

Your Profile:

  • For this position, we are looking for a PhD with either a background in or good knowledge of bioinformatics, preferably with experience in working with large-scale whole genome/exome datasets as well as mutational analyses.
  • The ideal candidate is tech-savvy, detail-oriented and diligent, with a general interest in cancer research, while he/she is friendly and open to work in a young and energetic research group.

We offer:

  • Access to large, primary patient sequencing datasets
  • Strong connection between dry- and wet-lab
  • Interesting work environment with „state of the art“ techniques
  • Friendly and open minded Team
  • International work environment through multiple European and international collaborations (travelling activities)
  • flexible working hours and various opportunities to reconcile work and private life
  • Good training opportunities

Women are encouraged to apply. Disabled persons with equal qualification will be preferred.

We kindly ask you to apply preferably via our online form to make the selection process faster and more effective. Of course, we also consider your written application without any disadvantages.

We look forward to receiving your application until May, 30th 2019, online with Registration number KIK0919573. For further Information please contact Dr. Franziska Auer by telephone 0351-458-4179 or by E-Mail: Franziska.Auer@uniklinikum-dresden.de