Benutzerspezifische Werkzeuge

Team

Prof. Dr. med. Stefan R. Bornstein
Prof. Bornstein is the director of the Medical Clinic III in Dresden and the main speaker of the KFO 252. Since last 15 years, he focuses his research on the interaction of the immune cells and inflammatory mediators with the HPA axis with particular interest in the adrenal gland. He provides an important expertise concerning the adrenal gland dysfunction in critical ill patients which is major topic of the project. In close collaboration with Prof. Zacharowski, he is responsible for discussion of experiments and data, and publication.

 

Prof. Kai Zacharowski, MD, PhD, FRCA
Kai is the director of the Clinic of Anaesthesiology, Intensive Care Medicine and Pain Therapy from the University Hospital of Frankfurt and co-investigator of this project in the Klinische Forschergruppe. As both clinician and researcher, he brings considerable expertise and clinical research experience related to systemic inflammatory response syndrome (SIRS) and sepsis. He provides important insight into clinical picture of critical ill patients at the intensive care unit which is crucial for the translational aspects of this project. In close collaboration with Prof. Bornstein, he is responsible for discussion of experiments and data, and publication.

 

Dr. rer. medic. Kanczkowski Waldemar
Waldemar is a young principal investigator in the group of Molecular Endocrinology Medical Clinic 3. His work focuses on the role of Innate Immunity in the adrenal gland dysfunction during LPS-mediated systemic inflammatory response syndrome and CLP-induced sepsis with a special focus on the involvement of endothelial and immune cells in this process. Furthermore, he studies the effect of cell-specific inactivation of TLR signaling within adrenal microenvironment in adrenal gland function and dysfunction during sepsis. He carries out the experiments involving primary cultures of human and murine adrenocortical cells. He is responsible for the supervision of the technician’s works, data acquisition and analysis. Finally he is responsible for communication of findings between the research groups in Frankfurt and Dresden and for publication of the results.

 

Dr. rer. med Carla Jennewein
Carla is a post-doctoral fellow of Prof. Zacharowski's research group in Frankfurt with strong background in inflammatory signaling. She carries out the performance of the mitochondrial studies as well as ROS analysis in CLP-treated mice. LUMINEX multiplex cytokine assays as well as expression analysis will also be performed in Frankfurt. . She is responsible for the supervision of the technician’s work, data acquisition and analysis as well as communication of findings between the two research groups.

 

Uta Lehnert
Uta is a technical assistant for the group. She is primary responsible for the experiments involving gene expression analysis, ELISAs and cell culture works. 

 

Vera Sprunck
Vera is a technical assistant for the group. Her primary responsibilities are to assist the animal experiments. Her secondary responsibilities include all routine methods of sample processing and analyses, e.g. immunhistology, determination of activity of respiratory chain components, ATP assays and ROS detection. realtime PCR, Western blotting etc.