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Publikationen

Publikationen

Clinicians and Scientists of the Saxonin Center for feto/neonatal Health do have a large international collaborative network. Results of the research collaboration have been published in various international journals. If you are interested to receive a PDF.file or to discuss published results, please do not hesitate to contact us.

2024

Stellungnahme – Zur neuen Mindestfallzahl für die Frühgeborenen-Versorgung

RÜDIGER, Mario; SCHLEUSSNER, Ekkehard. Statement-On the new minimum number of cases for premature baby care. GEBURTSHILFE UND FRAUENHEILKUNDE, 2024, 84. Jg., Nr. 02, S. 123-125.

Long-Term Outcome of Neonates and Infants whose Mothers Tested Positive for SARS-CoV-2 during Pregnancy – a Pilot of the Post-CRONOS Project

Mand N, König F, Pecks U, Keil CN, Backes C, Hütten M, Maier RF, Ruediger M. Long-Term Outcome of Neonates and Infants whose Mothers Tested Positive for SARS-CoV-2 during Pregnancy - a Pilot of the Post-CRONOS Project. Z Geburtshilfe Neonatol. 2024 Feb;228(1):97-101. English. doi: 10.1055/a-2213-9061. Epub 2024 Feb 8. PMID: 38330964.

Infant head and brain segmentation from magnetic resonance images using fusion-based deep learning strategies

Torres, Helena & Oliveira, Bruno & Morais, Pedro & Fritze, Anne & Hahn, Gabriele & Rüdiger, Mario & Fonseca, Jaime & Vilaça, João. (2024). Infant head and brain segmentation from magnetic resonance images using fusion-based deep learning strategies. Multimedia Systems. 30. 10.1007/s00530-024-01267-2. 

Single-Cell RNA Sequencing Reveals Repair Features of Human Umbilical Cord Mesenchymal Stromal Cells

Cyr-Depauw C, Cook DP, Mižik I, Lesage F, Vadivel A, Renesme L, Deng Y, Zhong S, Bardin P, Xu L, Möbius MA, Marzahn J, Freund D, Stewart DJ, Vanderhyden BC, Rüdiger M, Thébaud B. Single-Cell RNA Sequencing Reveals Repair Features of Human Umbilical Cord Mesenchymal Stromal Cells. Am J Respir Crit Care Med. 2024 Apr 2. doi: 10.1164/rccm.202310-1975OC. Epub ahead of print. PMID: 38564376.

Evaluation of the telemedical health care network "SAFE BIRTH" for pregnant women at risk, premature and sick newborns and their families: study protocol of a cluster-randomized controlled stepped-wedge trial

Hense H, Mathiebe J, Helfer S, Glaubitz R, Rüdiger M, Birdir C, Schmitt J, Müller G. Evaluation of the telemedical health care network "SAFE BIRTH" for pregnant women at risk, premature and sick newborns and their families: study protocol of a cluster-randomized controlled stepped-wedge trial. BMC Health Serv Res. 2024 Feb 14;24(1):200. doi: 10.1186/s12913-024-10667-z. PMID: 38355579; PMCID: PMC10865646.

Perinatal Networks: Ensuring Regional Care of Pregnant Woman and Newborns

Rüdiger M, Reichert J, Schmitt J, Birdir C. Perinatologische Kompetenznetzwerke: Die Versorgung von Schwangeren und Neugeborenen in einer Region [Perinatal Networks: Ensuring Regional Care of Pregnant Woman and Newborns]. Z Geburtshilfe Neonatol. 2024 Feb 16. German. doi: 10.1055/a-2211-7018. Epub ahead of print. PMID: 38365210.

Clinical consequences of maternal serum PAPP-A and free beta hCG levels above 2.0 multiple of median in the first trimester screening

Kosinski P, Frühauf A, Lipa M, Szczepkowska A, Luterek K, Falis M, Plaza O, Walasik I, Wielgos M, Wegrzyn P, Birdir C. Clinical consequences of maternal serum PAPP-A and free beta hCG levels above 2.0 multiple of median in the first trimester screening. Eur J Obstet Gynecol Reprod Biol. 2023 Mar;282:101-104. doi: 10.1016/j.ejogrb.2023.01.016. Epub 2023 Jan 21. PMID: 36706659.

Cleft lip and palate : One of the most frequent congenital malformations

Lauer G, Pradel W, Birdir C. Lippen-Kiefer-Gaumen-Spalte : Eine der häufigsten angeborenen Fehlbildungen [Cleft lip and palate : One of the most frequent congenital malformations]. HNO. 2023 Apr;71(4):276-284. German. doi: 10.1007/s00106-023-01291-0. PMID: 36897341.

SARS-CoV-2 Infection in Pregnancy and Incidence of Congenital Malformations - is there a Correlation? Analysis of 8032 Pregnancies from the CRONOS Registry

Hofbauer A, Schneider H, Kehl S, Reutter H, Pecks U, Andresen K, Morhart P; Collaborating authors. SARS-CoV-2-Infektion in der Schwangerschaft und Auftreten von angeborenen Fehlbildungen – Besteht ein Zusammenhang? Auswertung von 8032 Schwangerschaften aus dem CRONOS-Register [SARS-CoV-2 Infection in Pregnancy and Incidence of Congenital Malformations - is there a Correlation? Analysis of 8032 Pregnancies from the CRONOS Registry]. Z Geburtshilfe Neonatol. 2024 Feb;228(1):65-73. German. doi: 10.1055/a-2213-1506. Epub 2024 Feb 8. PMID: 38330961.

Smelling of the mothers' diet in amniotic fluid by adult noses

Gellrich J, Breidel P, Birdir C, Lohrer EC, Schriever VA. Smelling of the mothers' diet in amniotic fluid by adult noses. Chem Senses. 2024 Jan 31:bjae003. doi: 10.1093/chemse/bjae003. Epub ahead of print. PMID: 38297967.

Post-COVID in women after SARS-CoV-2 infection during pregnancy - a pilot study with follow-up data from the COVID-19-related Obstetric and Neonatal Outcome Study (CRONOS)

Backes C, Pecks U, Keil CN, Zöllkau J, Scholz C, Hütten M, Rüdiger M, Büchel J, Andresen K, Mand N. Post-COVID in women after SARS-CoV-2 infection during pregnancy - a pilot study with follow-up data from the COVID-19-related Obstetric and Neonatal Outcome Study (CRONOS). Z Geburtshilfe Neonatol. 2024 Feb;228(1):74-79. English. doi: 10.1055/a-2213-1665. Epub 2024 Feb 8. PMID: 38330962.

Adverse perinatal outcomes in gestational diabetes mellitus with and without SARS-CoV-2 infection during pregnancy: results from two nationwide registries in Germany

Liedtke TP, Weber KS, Adamczewski H, Weber D, Ramsauer B, Schaefer-Graf UM, Groten T, Strathmann EA, Lieb W, Rüdiger M, Pecks U, Kleinwechter HJ; CRONOS-GestDiab Collaboration. Adverse perinatal outcomes in gestational diabetes mellitus with and without SARS-CoV-2 infection during pregnancy: results from two nationwide registries in Germany. BMJ Open Diabetes Res Care. 2024 Jan 25;12(1):e003724. doi: 10.1136/bmjdrc-2023-003724. PMID: 38272538; PMCID: PMC10823927.

Detailed statistical analysis plan for ALBINO: effect of Allopurinol in addition to hypothermia for hypoxic-ischemic Brain Injury on Neurocognitive Outcome - a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III)

 Engel C, Rüdiger M, Benders MJNL, van Bel F, Allegaert K, Naulaers G, Bassler D, Klebermaß-Schrehof K, Vento M, Vilan A, Falck M, Mauro I, Metsäranta M, Vanhatalo S, Mazela J, Metsvaht T, van der Vlught R, Franz AR; ALBINO Study Group. Detailed statistical analysis plan for ALBINO: effect of Allopurinol in addition to hypothermia for hypoxic-ischemic Brain Injury on Neurocognitive Outcome - a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III). Trials. 2024 Jan 24;25(1):81. doi: 10.1186/s13063-023-07828-6. PMID: 38267942.

Vertical transmission of SARS-CoV-2 - data from the German COVID-19 related obstetric and neonatal outcome study (CRONOS)

Mand N, Rüdiger M, Hütten M, Maier RF, Mense L, Pecks U. Vertical transmission of SARS-CoV-2 - data from the German COVID-19 related obstetric and neonatal outcome study (CRONOS). J Perinat Med. 2024 Jan 5. doi: 10.1515/jpm-2023-0299. Epub ahead of print. PMID: 38175139.

2023

Vanilla odor promotes oral feeding in premature infants-A randomized controlled trial

Gellrich J, Messer V, Lohrer EC, Zickmüller C, Croy I, Schlage S, Rüdiger M, Schriever VA. Vanilla odor promotes oral feeding in premature infants-A randomized controlled trial. Physiol Behav. 2023 Nov 25;274:114417. doi: 10.1016/j.physbeh.2023.114417. Epub ahead of print. PMID: 38013048.

Similar adverse outcome rates with high or low oxygen saturation targets in an area with low background mortality

Willgerodt N, Bührer C, Rossi R, Kühn T, Rüdiger M, Avenarius S, Böttger R, Olbertz DM, Proquitte H, Bittrich HJ, Haase R, Fröhlich M, Höhne S, Thome UH. Similar adverse outcome rates with high or low oxygen saturation targets in an area with low background mortality. Front Pediatr. 2023 Oct 24;11:1235877. doi: 10.3389/fped.2023.1235877. PMID: 37941976; PMCID: PMC10628636.

2023 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces

Berg KM, Bray JE, Ng KC, Liley HG, Greif R, Carlson JN, Morley PT, Drennan IR, Smyth M, Scholefield BR, Weiner GM, Cheng A, Djärv T, Abelairas-Gómez C, Acworth J, Andersen LW, Atkins DL, Berry DC, Bhanji F, Bierens J, Bittencourt Couto T, Borra V, Böttiger BW, Bradley RN, Breckwoldt J, Cassan P, Chang WT, Charlton NP, Chung SP, Considine J, Costa-Nobre DT, Couper K, Dainty KN, Dassanayake V, Davis PG, Dawson JA, de Almeida MF, De Caen AR, Deakin CD, Dicker B, Douma MJ, Eastwood K, El-Naggar W, Fabres JG, Fawke J, Fijacko N, Finn JC, Flores GE, Foglia EE, Folke F, Gilfoyle E, Goolsby CA, Granfeldt A, Guerguerian AM, Guinsburg R, Hatanaka T, Hirsch KG, Holmberg MJ, Hosono S, Hsieh MJ, Hsu CH, Ikeyama T, Isayama T, Johnson NJ, Kapadia VS, Kawakami MD, Kim HS, Kleinman ME, Kloeck DA, Kudenchuk P, Kule A, Kurosawa H, Lagina AT, Lauridsen KG, Lavonas EJ, Lee HC, Lin Y, Lockey AS, Macneil F, Maconochie IK, Madar RJ, Malta Hansen C, Masterson S, Matsuyama T, McKinlay CJD, Meyran D, Monnelly V, Nadkarni V, Nakwa FL, Nation KJ, Nehme Z, Nemeth M, Neumar RW, Nicholson T, Nikolaou N, Nishiyama C, Norii T, Nuthall GA, Ohshimo S, Olasveengen TM, Ong YG, Orkin AM, Parr MJ, Patocka C, Perkins GD, Perlman JM, Rabi Y, Raitt J, Ramachandran S, Ramaswamy VV, Raymond TT, Reis AG, Reynolds JC, Ristagno G, Rodriguez-Nunez A, Roehr CC, Rüdiger M, Sakamoto T, Sandroni C, Sawyer TL, Schexnayder SM, Schmölzer GM, Schnaubelt S, Semeraro F, Singletary EM, Skrifvars MB, Smith CM, Soar J, Stassen W, Sugiura T, Tijssen JA, Topjian AA, Trevisanuto D, Vaillancourt C, Wyckoff MH, Wyllie JP, Yang CW, Yeung J, Zelop CM, Zideman DA, Nolan JP; Collaborators. 2023 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces. Circulation. 2023 Nov 9. doi: 10.1161/CIR.0000000000001179. Epub ahead of print. PMID: 37942682.

 2023 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces.

Berg KM, Bray JE, Ng KC, Liley HG, Greif R, Carlson JN, Morley PT, Drennan IR, Smyth M, Scholefield BR, Weiner GM, Cheng A, Djärv T, Abelairas-Gómez C, Acworth J, Andersen LW, Atkins DL, Berry DC, Bhanji F, Bierens J, Bittencourt Couto T, Borra V, Böttiger BW, Bradley RN, Breckwoldt J, Cassan P, Chang WT, Charlton NP, Chung SP, Considine J, Costa-Nobre DT, Couper K, Dainty KN, Dassanayake V, Davis PG, Dawson JA, Fernanda de Almeida M, De Caen AR, Deakin CD, Dicker B, Douma MJ, Eastwood K, El-Naggar W, Fabres JG, Fawke J, Fijacko N, Finn JC, Flores GE, Foglia EE, Folke F, Gilfoyle E, Goolsby CA, Granfeldt A, Guerguerian AM, Guinsburg R, Hatanaka T, Hirsch KG, Holmberg MJ, Hosono S, Hsieh MJ, Hsu CH, Ikeyama T, Isayama T, Johnson NJ, Kapadia VS, Daripa Kawakami M, Kim HS, Kleinman ME, Kloeck DA, Kudenchuk P, Kule A, Kurosawa H, Lagina AT, Lauridsen KG, Lavonas EJ, Lee HC, Lin Y, Lockey AS, Macneil F, Maconochie IK, John Madar R, Malta Hansen C, Masterson S, Matsuyama T, McKinlay CJD, Meyran D, Monnelly V, Nadkarni V, Nakwa FL, Nation KJ, Nehme Z, Nemeth M, Neumar RW, Nicholson T, Nikolaou N, Nishiyama C, Norii T, Nuthall GA, Ohshimo S, Olasveengen TM, Gene Ong YK, Orkin AM, Parr MJ,…See abstract for full author list ➔Resuscitation. 2023 Nov 7:109992. doi: 10.1016/j.resuscitation.2023.109992. Online ahead of print.PMID: 37937881

COVID-19, Pregnancy, and Diabetes Mellitus.

 Kleinwechter HJ, Weber KS, Liedtke TP, Schäfer-Graf U, Groten T, Rüdiger M, Pecks U.Z Geburtshilfe Neonatol. 2023 Nov 2. doi: 10.1055/a-2180-7715. Online ahead of print.PMID: 37918833 English.

How should we perform neonatal mask ventilation during MR SOPA corrective steps? 

Mileder LP, Wagner M, Kaufmann M, Gaertner VD, Rüegger CM, Springer L. Resusc Plus. 2023 Feb 25;13:100344. doi: 10.1016/j.resplu.2022.100344. eCollection 2023 Mar. PMID: 36915915 Free PMC article. No abstract available.

Parental perspectives about information and deferred versus two-stage consent in studies of neonatal asphyxia. 

Maiwald CA, Rovers C, Janvier A, Sturm H, Michaelis M, Marckmann G, Ehni HJ, Poets CF, Rüdiger M, Franz AR.Arch Dis Child Fetal Neonatal Ed. 2023 Aug 30:fetalneonatal-2023-325900. doi: 10.1136/archdischild-2023-325900. Online ahead of print.PMID: 37648417

Proceedings of the 14th International Newborn Brain Conference: Other forms of brain monitoring, such as NIRS, fMRI, biochemical, etc. 

Ali S, Altamimi T, Annink K, Bartmann P, Beato N, Belker K, Ben-David D, Benders M, Bhattacharya S, Anbu Chakkarapani A, Anbu Chakkarapani A, Charbonneau L, Cherkerzian S, Chowdhury RA, Christou H, de Ribaupierre D, Dehaes M, Domogalla C, Duerden EG, El-Dib M, Elanbari M, Elshibiny H, Engel C, Felderhoff U, Flemmer AW, Franceschini MA, Franz A, Garvey A, Groenendaal F, Gupta S, Hannon K, Hellström-Westas L, Herber-Jonat S, Holz S, Hüning B, Inder T, Jamil A, Jilson T, Kebaya LMN, Keller M, Khalifa AKM, Kim SH, Kittel J, Koch L, Kowalczyk A, Kühr J, St Lawrence K, Lee S, Marandyuk B, Marlow N, Mayorga PC, Meyer R, Meyerink P, Miró J, More K, Munk A, Munster C, Musabi M, Nuyt AM, Peters J, Plum A, Poirier N, Pöschl J, Raboisson MJ, Robinson J, Roychaudhuri S, Rüdiger M, Sarközy G, Saugstad OD, Segerer H, Soni N, Stein A, Steins-Rang C, Sunwoo J, Szakmar E, Tang L, Taskin E, Vahidi H, Waldherr S, Wieg C, Winkler S, Wu R, Yajamanyam PK, Yapicioglu-Yildizdas H.J Neonatal Perinatal Med. 2023;16(s1):S63-S73. doi: 10.3233/NPM-239004.PMID: 37599543 

Predicting adverse outcomes in pregnant patients positive for SARS-CoV-2: a machine learning approach- a retrospective cohort study.

Young D, Houshmand B, Tan CC, Kirubarajan A, Parbhakar A, Dada J, Whittle W, Sobel ML, Gomez LM, Rüdiger M, Pecks U, Oppelt P, Ray JG, Hobson SR, Snelgrove JW, D'Souza R, Kashef R, Sussman D.BMC Pregnancy Childbirth. 2023 Aug 2;23(1):553. doi: 10.1186/s12884-023-05679-2.PMID: 37532986

Vertical transmission of SARS-CoV-2 - are there differences in rates of neonatal SARS-CoV-2 infection in two classification systems?. 

Mand N, Hutten M, Maier RF, Mense L, Pecks U, Rüdiger M; CRONOS Network. Arch Dis Child Fetal Neonatal Ed. 2023 Jul 7:fetalneonatal-2023-325835. doi: 10.1136/archdischild-2023-325835. Online ahead of print.

2022

 2022 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces. Wyckoff MH, Greif R, Morley PT, ... Roehr CC, Rüdiger M, ... , Berg KM; Collaborators.Resuscitation. 2022 Dez;181:208-288. doi: 10.1016/j.resuscitation.2022.10.005. Epub 2022 Nov 3. 
 
Geburtshilfe und Neonatologie 2022; 226(05): 354 - 355. doi: 10.1055/a-1913-3717
    
Is Fetal Hydrops in Turner Syndrome a Risk Factor for the Development of Maternal Mirror Syndrome?
Bedei IA, Graf A, Gloning KP, Meyer-Wittkopf M, Willner D, Krapp M, Hentze S, Scharf A, Degenhardt J, Heling KS, Kozlowski P, Trautmann K, Jahns K, Geipel A, Tekesin I, Elsässer M, Wilhelm L, Gottschalk I, Baumüller JE, Birdir C, Zöllner F, Wolter A, Schenk J, Gehrke T, Keil C, Espinosa J, Axt-Fliedner R.J Clin Med. 2022 Aug 5;11(15):4588. doi: 10.3390/jcm11154588.
 
Suctioning of clear amniotic fluid at birth: A systematic review.Fawke J, Wyllie J, Udaeta E, Rüdiger M, Ersdal H, Wright MD, Wyckoff MH, Liley HG, Rabi Y, Weiner GM; International Liaison Committee On Resuscitation Neonatal Life Support Task Force.Resusc Plus. 2022 Sep 17;12:100298. doi: 10.1016/j.resplu.2022.100298. eCollection 2022 Dec
 

Future of clinical trials in the delivery room: time for pragmatism. O'Donnell CPF, Dekker J, Rüdiger M, Te Pas AB.Arch Dis Child Fetal Neonatal Ed. 2022 Sep 26:fetalneonatal-2022-324387. doi: 10.1136/archdischild-2022-324387. Online ahead of print.

3D Facial Landmark Localization for cephalometric analysis. Torres HR, Morais P, Fritze A, Oliveira B, Veloso F, Rudiger M, Fonseca JC, Vilaca JL.Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:1016-1019. doi: 10.1109/EMBC48229.2022.9871184

Semi-mechanistic Modeling of Hypoxanthine, Xanthine, and Uric Acid Metabolism in Asphyxiated Neonates. Chu WY, Allegaert K, Dorlo TPC, Huitema ADR; ALBINO Study Group.Clin Pharmacokinet. 2022 Nov;61(11):1545-1558. doi: 10.1007/s40262-022-01164-9. Epub 2022 Aug 30. 

Association of Administration of Surfactant Using Less Invasive Methods With Outcomes in Extremely Preterm Infants Less Than 27 Weeks of Gestation. Härtel C, Herting E, Humberg A, Hanke K, Mehler K, Keller T, Mauer I, Frieauff E, Meyer S, Thome UH, Wieg C, Schmidtke S, Kribs A, Göpel W; German Neonatal Network.JAMA Netw Open. 2022 Aug 1;5(8):e2225810. doi: 10.1001/jamanetworkopen.2022.25810.

Restrictive prescription of antibiotics in preterm infants with premature rupture of membranes. Armann J, Rüdiger M, Berner R, Mense L.BMC Pediatr. 2022 Jul 12;22(1):408. doi: 10.1186/s12887-022-03476-y.

SARS-CoV-2 Infection During Pregnancy-An Analysis of Clinical Data From Germany and Austria From the CRONOS Registry. Pecks U, Mand N, Kolben T, Rüdiger M, Oppelt P, Zöllkau J, Dempfle A; CRONOS Network.Dtsch Arztebl Int. 2022 Sep 5;119(35-36):588-594. doi: 10.3238/arztebl.m2022.0266. PMID: 35794736. 

Realistic 3D infant head surfaces augmentation to improve AI-based diagnosis of cranial deformities. Torres HR, Oliveira B, Morais P, Fritze A, Rüdiger M, Fonseca JC, Vilaça JL.J Biomed Inform. 2022 Aug;132:104121. doi: 10.1016/j.jbi.2022.104121. Epub 2022 Jun 22. PMID: 35750261.

Anthropometric Landmarking for Diagnosis of Cranial Deformities: Validation of an Automatic Approach and Comparison with Intra- and Interobserver Variability.Torres HR, Morais P, Fritze A, Burkhardt W, Kaufmann M, Oliveira B, Veloso F, Hahn G, Rüdiger M, Fonseca JC, Vilaça JL.Ann Biomed Eng. 2022 May 27. doi: 10.1007/s10439-022-02981-6. Epub 2022 May 27. PMID: 35622207.

Gestational diabetes mellitus and COVID-19: results from the CRONOS study.Kleinwechter HJ, Weber KS, Mingers N, Ramsauer B, Schaefer-Graf UM, Groten T, Kuschel B, Backes C, Banz-Jansen C, Berghaeuser MA, Brotsack IA, Dressler-Steinbach I, Engelbrecht C, Engler-Hauschild S, Gruber TM, Hepp V, Hollatz-Galuschki E, Iannaccone A, Jebens A, VON Kaisenberg CS, Kaup L, Keil C, Kladt C, Kolben T, Kraft K, Kunze M, Lastinger J, Luedemann K, Manz J, Morfeld CA, Parchmann O, Pfaff L, Reinhardt K, Runkel A, Schmidt M, Sourouni M, Stelbrink J, Stubert J, Stumpfe FM, Treptow A, Rüdiger M, Pecks U; CRONOS Network.Am J Obstet Gynecol. 2022 May 14:S0002-9378(22)00372-6. doi: 10.1016/j.ajog.2022.05.027.

Physiologie-basiertes Abnabeln bei Frühgeborenen. Neonatologische Erstversorgung noch vor dem Abnabeln.
Pecqueux E, Winkler J, Mense L, Seipolt B, Wimberger P, Rüdiger M, Birdir C. Frauenarzt. 2022 Apr;63:234-237.  

Fetal head circumference delineation using convolutional neural networks with registration-based ellipse fitting HR Torres, B Oliveira, PR Morais, A Fritze, C Birdir, M Rüdiger, Jaime C Fonseca, João L Vilaça. Medical Imaging:Image Processing 2022:12032, 927-933, https://doi.org/10.1117/12.2611150

Pulmonary and Neurologic Effects of Mesenchymal Stromal Cell Extracellular Vesicles in a Multifactorial Lung Injury Model.  Lithopoulos MA, Strueby L, O'Reilly M, Zhong S, Möbius MA, Eaton F, Fung M, Hurskainen M, Cyr-Depauw C, Suen C, Xu L, Collins JJP, Vadivel A, Stewart DJ, Burger D, Thébaud B.Am J Respir Crit Care Med. 2022 May 15;205(10):1186-1201. doi: 10.1164/rccm.202012-4520OC.

Perinatal Hyperoxia and Developmental Consequences on the Lung-Brain Axis.Obst S, Herz J, Alejandre Alcazar MA, Endesfelder S, Möbius MA, Rüdiger M, Felderhoff-Müser U, Bendix I.Oxid Med Cell Longev. 2022 Feb 24;2022:5784146. doi: 10.1155/2022/5784146. eCollection 2022.

The newborn delivery room of tomorrow: emerging and future technologies. Batey N, Henry C, Garg S, Wagner M, Malhotra A, Valstar M, Smith T, Sharkey D; European Society for Paediatric Research (ESPR) Neonatal Resuscitation Section Writing Group.Pediatr Res. 2022 Mar 3. doi: 10.1038/s41390-022-01988-y. Online ahead of print.

Efficacy and Safety of Enteral Recombinant Human Insulin in Preterm Infants: A Randomized Clinical Trial.Mank E, Sáenz de Pipaón M, Lapillonne A, Carnielli VP, Senterre T, Shamir R, van Toledo L, van Goudoever JB; FIT-04 Study Group.JAMA Pediatr. 2022 May 1;176(5):452-460. doi: 10.1001/jamapediatrics.2022.0020. Epub 2022 Feb 28.

Tactile stimulation in the delivery room: past, present, future. A systematic review. Kaufmann M, Mense L, Springer L, Dekker J.Pediatr Res. 2022 Feb 5. doi: 10.1038/s41390-022-01945-9. Online ahead of print.

Pregnant and Postpartum WomenRequiring Intensive Care Treatmentfor COVID-19—First Data from theCRONOS-Registry. Sitter, M.; Pecks, U.;Rüdiger, M.; Friedrich, S.; FillMalfertheiner, S.; Hein, A.;Königbauer, J.T.; Becke-Jakob, K.;Zöllkau, J.; Ramsauer, B.; et al. J. Clin. Med. 2022,11, 701.  https://doi.org/10.3390/jcm11030701.

A review of image processing methods for fetal head and brain analysis in ultrasound images.Torres HR, Morais P, Oliveira B, Birdir C, Rüdiger M, Fonseca JC, Vilaça JL.Comput Methods Programs Biomed. 2022 Mar;215:106629. doi: 10.1016/j.cmpb.2022.106629. Epub 2022 Jan 13.

Functional morphometry to estimate the alveolar surface area by using a premature baboon model. Dassios T, Rüdiger M, McCurnin D, Seidner SR, Williams EE, Greenough A, Möbius MA.J Appl Physiol. 2022 Jan 1;132(1):209-215. doi: 10.1152/japplphysiol.00644.2021.

2021

A critical appraisal of tools for delivery room assessment of the newborn infant. Niemuth M, Küster H, Simma B, Rozycki H, Rüdiger M; European Society for Paediatric Research (ESPR) Neonatal Resuscitation Section Writing Group, Solevåg AL.Pediatr Res. 2021 Dec 30. doi: 10.1038/s41390-021-01896-7. Online ahead of print.

Video recording in the delivery room: current status, implications and implementation.  Simma B, den Boer M, Nakstad B, Küster H, Herrick HM, Rüdiger M, Aichner H, Kaufmann M.Pediatr Res. 2021 Nov 24. doi: 10.1038/s41390-021-01865-0. Online ahead of print.

Prenatal diagnosis of exomphalos and prediction of outcome. Nitzsche K, Fitze G, Rüdiger M, Wimberger P, Birdir C.Sci Rep. 2021 Apr 22;11(1):8752. doi: 10.1038/s41598-021-88245-0.
 

Systematic analysis of candidate reference genes for gene expression analysis in hyperoxia-based mouse models of bronchopulmonary dysplasia.Linge M, Möbius MA, Rösen-Wolff A, Winkler S.Am J Physiol Lung Cell Mol Physiol. 2021 Oct 1;321(4):L718-L725. doi: 10.1152/ajplung.00143.2021. Epub 2021 Aug 11.

Pharmacokinetic/Pharmacodynamic Modelling of Allopurinol, its Active Metabolite Oxypurinol, and Biomarkers Hypoxanthine, Xanthine and Uric Acid in Hypoxic-Ischemic Encephalopathy Neonates.Chu WY, Annink KV, Nijstad AL, Maiwald CA, Schroth M, Bakkali LE, van Bel F, Benders MJNL, van Weissenbruch MM, Hagen A, Franz AR, Dorlo TPC, Allegaert K, Huitema ADR; ALBINO Study Group.Clin Pharmacokinet. 2022 Feb;61(2):321-333.doi: 10.1007/s40262-021-01068-0. Epub 2021 Oct 7.

Course of the sFlt-1/PlGF ratio in fetal growth restriction and correlation with biometric measurements, feto-maternal Doppler parameters and time to delivery. Andrikos A, Andrikos D, Schmidt B, Birdir C, Kimmig R, Gellhaus A, Köninger A.Arch Gynecol Obstet. 2022 Mar;305(3):597-605. doi: 10.1007/s00404-021-06186-5. Epub 2021 Aug 25. PMID: 34432111.

Peripheral Arterial Lines in Extremely Preterm Neonates: A Potential Alternative to Umbilical Arterial Catheters. Mense L, Rose S, Bruck A, Rüdiger M, Kaufmann M, Seipolt B.Adv Neonatal Care. 2022 Aug 1;22(4):357-361. doi: 10.1097/ANC.0000000000000909. Epub 2021 Jul 30. PMID:34334679.

Anthropometric Landmark Detection in 3D Head Surfaces Using a Deep Learning Approach. Torres HR; Morais P; Fritze A; Oliveira B; Veloso F; Rüdiger M; Fonseca JC; Vilaca JL; IEEE J Biomed Health Inform. 2021 July, 25:7; doi: 10.1109/JBHI.2020.3035888.

Are birth outcomes in low risk birth cohorts related to hospital birth volumes? A systematic review. Walther F, Kuester D, Bieber A, Malzahn J, Rüdiger M, Schmitt J. BMC Pregnancy Childbirth. 2021 Jul 27;21(1):531. doi: 10.1186/s12884-021-03988-y.

Neonatal outcome following maternal infection with SARS-CoV-2 in Germany: COVID-19-Related Obstetric and Neonatal Outcome Study (CRONOS). Mand N, Iannaccone A, Longardt AC, Hutten M, Mense L, Oppelt P, Maier RF, Pecks U, Rüdiger M; CRONOS Network; CRONOS-Network. Arch Dis Child Fetal Neonatal Ed. 2022 Jul;107(4):454-456. doi: 10.1136/archdischild-2021-322100. Epub 2021 Jul 19. PMID: 34281935.

Reference Charts for Neonatal Cranial Volume Based on 3D Laser Scanning to Monitor Head Growth. Vermeulen MJ, Burkhardt W, Fritze A, Roelants J, Mense L, Willemsen S, Rüdiger M.Front Pediatr. 2021 May 28;9:654112. doi: 10.3389/fped.2021.654112. eCollection 2021.

Prenatal Methamphetamine Exposure: Effects on Child Development. Harst L, Deckert S, Haarig F, Reichert J, Dinger J, Hellmund P, Schmitt J, Rüdiger M.Dtsch Arztebl Int. 2021 May 7;118(18):313-319. doi: 10.3238/arztebl.m2021.0128.

Are two children at once better than one? Risk analysis of twin pregnancies and births after assisted reproduction. Goeckenjan M, Madej D, Klimova A, Wimberger P, Birdir C, Glaß K. Eur J Obstet Gynecol Reprod Biol. 2021 Sep;264:76-82. doi: 10.1016/j.ejogrb.2021.06.047. Epub 2021 Jul 4.

Reply letter to: Intubation in neonatal resuscitation - compelling necessity or incalculable risk? Roehr CC, Madar J, Morley CJ, Ainsworth S, Ersdal H, Rüdiger M, Skåre C, Szczapa T, Te Pas A, Trevisanuto D, Urlesberger B, Wilkinson D, Wyllie JP; ERC-NLS 2021 writing group. Resuscitation. 2021 Jun 2:S0300-9572(21)00206-9. doi: 10.1016/j.resuscitation.2021.05.022.

[Newborn resuscitation and support of transition of infants at birth].Madar J, Roehr CC, Ainsworth S, Ersda H, Morley C, Rüdiger M, Skåre C, Szczapa T, Te Pas A, Trevisanuto D, Urlesberger B, Wilkinson D, Wyllie JP.Notf Rett Med. 2021;24(4):603-649. German. doi: 10.1007/s10049-021-00894-w. Epub 2021 Jun 2. PMID: 34093078.

Mother's Own Milk Feeding in Preterm Newborns Admitted to the Neonatal Intensive Care Unit or Special-Care Nursery: Obstacles, Interventions, Risk Calculation.Heller N, Rüdiger M, Hoffmeister V, Mense L.Int J Environ Res Public Health. 2021 Apr 14;18(8):4140. doi: 10.3390/ijerph18084140.

Auswirkungen von SARS-CoV-2 auf Schwangere und deren Neugeborene. Rüdiger M., Pecks U.  Connexiplus. 2021; 1; 48-55.

European Resuscitation Council Guidelines 2021: Newborn resuscitation and support of transition of infants at birth. Madar J, Roehr CC, Ainsworth S, Ersdal H, Morley C, Rüdiger M, Skåre C, Szczapa T, Te Pas A, Trevisanuto D, Urlesberger B, Wilkinson D, Wyllie JP. Resuscitation. 2021 Apr;161:291-326. doi: 10.1016/j.resuscitation.2021.02.014. Epub 2021 Mar 24.

Glomerular Filtration Rate in Asphyxiated Neonates Under Therapeutic Whole-Body Hypothermia, Quantified by Mannitol Clearance. Deferm N, Annink KV, Faelens R, Schroth M, Maiwald CA, Bakkali LE, van Bel F, Benders MJNL, van Weissenbruch MM, Hagen A, Smits A, Annaert P, Franz AR, Allegaert K; ALBINO Study Group. Clin Pharmacokinet. 2021 Jul;60(7):897-906. doi: 10.1007/s40262-021-00991-6. Epub 2021 Feb 21.

[Association between Socioeconomic Status and Developmental Status: Data Linkage of Results of the Daycare and School Entry Health Examinations of a Saxon Birth Cohort Study]. Redemann D, Arnold K, Druschke D, Heinrich L, Rüdiger M, Reichert J, Schmitt J.Gesundheitswesen. 2021 Mar;83(3):222-230. German. doi: 10.1055/a-1327-2463. Epub 2021 Jan 25. PMID: 33494112.

Roland R. Wauer (1942-2020): neonatologist, scientist, teacher and visionary. Rüdiger M, Reichert J, Proquitte H, Schmalisch G, Hammer H, Weigel H, Wilitzki S, Fentsch P, Roehr CC.Pediatr Res. 2021 Sep;90(3):703-704. doi: 10.1038/s41390-020-01338-w. Epub 2021 Jan 14. PMID: 33446926.

Obstetric forceps dimensions and the newborn head biometry: Time for an update. Ismail AT, Fritze A, Rüdiger M,  Isamil KMEur J Obstet Gynecol Reprod Biol. 2021 Jan;256:270-273. doi: 10.1016/j.ejogrb.2020.11.046.

2019/ 2020

2020

Pregnancy and SARS-CoV-2 Infection in Germany-the CRONOS Registry. Pecks U, Kuschel B, Mense L, Oppelt P, Rüdiger M; CRONOS Network.Pec Dtsch Arztebl Int. 2020 Dec 4;117(49):841-842. doi: 10.3238/arztebl.2020.0841.

Placenta accreta spectrum disorders-experience of management in a German tertiary perinatal centre. Bluth A, Schindelhauer A, Nitzsche K, Wimberger P, Birdir C. Arch Gynecol Obstet. 2021 Jun;303(6): 1451 - 1460. doi: 10.1007/s00404-020-05875-x. Epub 2020 Dec 7.

Evaluation of carcinoembryonic antigen-related cell adhesion molecule 1 blood serum levels in women at high risk for preeclampsia.  Mach P, Andrikos D, Schmidt B, Gellhaus A, Rusch P, Birdir C, Andrikos A, Schmitt V, Kimmig R, Singer BB, Köninger A. Am J Reprod Immunol. 2021 May;85(5):e13375. doi: 10.1111/aji.13375. Epub 2020 Nov 25.

Results of the hypothermia registry of the University Hospital Dresden from 2010-2017. Application of hypothermia therapy in newborns in Germany. Scherer J, Whybra-Trümpler C, Mildenberger E Z Geburtshilfe Neonatol. 2020 Dec;224(6):367-373. doi: 10.1055/a-1164-7174.   
   

CRONOS-Netzwerk: Pregnancy and SARS CoV-2 infection in Germany - the CRONOS registry. Peck U, Kuschel B, Mense L, Oppelt P, Rüdiger M. Dtsch Arztebl Int 2020;117: 841-2. DOI: 10.3238/ arztebl.2020.0841.

Anthropometric Landmark Detection in 3D Head Surfaces using a Deep Learning Approach. Torres HR; Morais P; Fritze A; Oliveira B; Veloso F; Rüdiger M; Fonseca JC; Vilaca JL; IEEE J Biomed Health Inform. 2021 Jul;25(7): 2643 - 2654. doi: 10.1109/JBHI.2020.3035888. PMID: 33147152. 2020 Nov 4.

Neonatal Life Support: 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Wyckoff MH, Wyllie J, Aziz K, de Almeida MF, Fabres J, Fawke J, Guinsburg R, Hosono S, Isayama T, Kapadia VS, Kim HS, Liley HG, McKinlay CJD, Mildenhall L, Perlman JM, Rabi Y, Roehr CC, Schmölzer GM, Szyld E, Trevisanuto D, Velaphi S, Weiner GM; Neonatal Life Support Collaborators.Wyckoff MH, et al. Circulation. 2020 Oct 20;142(16_suppl_1):S185-S221. doi: 10.1161/CIR.0000000000000895.

 Neonatal Life Support 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Wyckoff MH, Wyllie J, Aziz K, de Almeida MF, Fabres JW, Fawke J, Guinsburg R, Hosono S, Isayama T, Kapadia VS, Kim HS, Liley HG, McKinlay CJD, Mildenhall L, Perlman JM, Rabi Y, Roehr CC, Schmölzer GM, Szyld E, Trevisanuto D, Velaphi S, Weiner GM; Neonatal Life Support Collaborators. Resuscitation. 2020 Nov;156:A156-A187. doi: 10.1016/j.resuscitation.2020.09.015.

Impact of regionalisation and case-volume on neonatal and perinatal mortality: an umbrella review. Walther F, Küster DB, Bieber A, Rüdiger M, Malzahn J, Schmitt J, Deckert S. BMJ Open. 2020 Sep 25;10(9):e037135. doi: 10.1136/bmjopen-2020-037135

Apgar Score-It Is Time to Avoid Pain-Reply. Rüdiger M, Rozycki HJ JAMA Pediatr. 2020 Sep 14. doi: 10.1001/jamapediatrics.2020.2560. 

Effects of Liberal vs Restrictive Transfusion Thresholds on Survival and Neurocognitive Outcomes in Extremely Low-Birth-Weight Infants: The ETTNO Randomized Clinical Trail. Franz AR, Engel C, Bassler D, Rüdiger M, Thome UH, Maier RF, Krägeloh-Mann I, Kron M, Essers J, Bührer C, Rellensmann G, Rossi R, Bittrich HJ, Roll C, Höhn T, Ehrhardt H, Avenarius S, Körner HT, Stein A, Buxmann H, Vochem M, Poets CF; ETTNO Investigators. JAMA. 2020 Aug 11;324(6):560-570. doi: 10.1001/jama.2020.10690

MR-proANP, a cardiovascular biomarker to predict late-onset preeclampsia and intrauterine growth restricted fetuses. Birdir C, Fox L, Droste L, Frank M, Fryze J, Enekwe A, Köninger A, Kimmig R, Schmidt B, Gellhaus A. Pregnancy Hypertens. 2020 Jul 13;22:54-58. doi: 10.1016/j.preghy.2020.07.004. 

Prenatal Prediction of Outcome by Fetal Gasteoschisis in a Tertiary Referral Center. Nitzsche K, Fitze G, Rüdiger M, Birdir C.Diagnostics (Basel). 2020 Jul 30;10(8):540. doi: 10.3390/diagnostics10080540

Newborn care and life support. Madar J, Roehr C, Ainsworth S, Ersdal H, Morley C, Rüdiger M, Skåre C, Szczapa T, Te Pas A, Trevisanuto D, Urlesberger B, Wilkinson D, Wyllie J.Notf Rett Med. 2020;23(4):257-259. doi: 10.1007/s10049-020-00722-7.

European Resuscitation Council COVID-19 guidelines executive summary. Nolan JP, Monsieurs KG, Bossaert L, Böttiger BW, Greif R, Lott C, Madar J, Olasveengen TM, Roehr CC, Semeraro F, Soar J, Van de Voorde P, Zideman DA, Perkins GD; European Resuscitation Council COVID-Guideline Writing Groups. Resuscitation. 2020 Aug;153:45-55. doi: 10.1016/j.resuscitation.2020.06.001

Neonatal and young infant sepsis by Group B Streptococci and Escherichia coli: a single-center retrospective analysis in Germany-GBS screening implementation gaps and reduction in antibiotic resistance. Doenhardt M, Seipolt B, Mense L, Winkler JL, Thürmer A, Rüdiger M, Berner R, Armann J. Eur J Pediatr. 2020 Nov;179(11):1769-1777. doi: 10.1007/s00431-020-03659-8. Epub 2020 May 23.

Delivery Room Management of Infants with Very Low Birth Weight in 3 European Countries - Theo Video Study. Simma B, Walter S, Konstantelos D, van Vonderen J, Te Pas AB, Rüdiger M, Küster H. J Pediatr. 2020 Jul;222:106-111.e2. doi: 10.1016/j.jpeds.2020.03.035. Epub 2020 May 14.

Individual-Level Linkage of Primary and Secondary Data from Three Sources for Comprehensive Analyses of Low Birthweight Effects. Druschke D, Arnold K, Heinrich L, Reichert J, Rüdiger M, Schmitt J. Gesundheitswesen. 2020 Mar;82(S 02):S108-S116. doi: 10.1055/a-1082-0740. Epub 2020 Mar 19.

It`s Time to Reevaluate the Apgar Score. Rüdiger M, Rozycki HJ. JAMA Pediatr. 2020 Apr 1;174(4):321-322. doi: 10.1001/jamapediatrics.2019.6016.

Surgical necrotizing enterocolitis but not spontaneous intestinal perforation is associated with adverse neurological outcome at school age. Humberg A, Spiegler J, Fortmann MI, Zemlin M, Marissen J, Swoboda I, Rausch TK, Herting E, Göpel W, Härtel C; German Neonatal Network (GNN). Sci Rep. 2020 Feb 11;10(1):2373. doi: 10.1038/s41598-020-58761-6.

How to introduce MSC-based therapy for the developing lung safely into clinical care? Rüdiger M, Kirpalani H, Steinhorn R, Davis JM, Thebaud B. Pediatr Res. 2020 Sep;88(3):365-368. doi: 10.1038/s41390-020-0758-0.

Intrauterine Growth Restriction: Transsectoral, Interdisciplinary and Multiprofessional Care for Pregnant Women and Newborns in a Feto-neonatal Pathway: A project of the Innovationsfonds. Mense L, Birdir C, Reichert J, Schleußner E, Proquitté H, Schmitt J, Müller G, Rüdiger M. Z Geburtshilfe Neonatol. 2020 Feb;224(1):15-21. doi: 10.1055/a-0998-4532.

Hospital survey showed wide variations in therapeutic hypothermia for neonates in Germany. Giannakis S, Ruhfus M, Rüdiger M, Sabir H; German Neonatal Hypothermia Network. Acta Paediatr. 2020 Jan;109(1):200-201. doi: 10.1111/apa.14979

Late Rescue Therapy with Cord-Derived Mesenchymal Stromal Cells for Established Lung Injury in Experimental Bronchopulmonary Dysplasia. O'Reilly M, Möbius MA, Vadivel A, Ionescu L, Fung M, Eaton F, Greer JJ, Thébaud B. Stem Cells Dev. 202

2019 

Effect of allopurinol in addition to hypothermia treatment in neonates for hypoxic-ischemic brain injury on neurocognitive outcome (ALBINO): study protocol of a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III). Maiwald CA, Annink KV, Rüdiger M, Benders MJNL, van Bel F, Allegaert K, Naulaers G, Bassler D, Klebermaß-Schrehof K, Vento M, Guimarães H, Stiris T, Cattarossi L, Metsäranta M, Vanhatalo S, Mazela J, Metsvaht T, Jacobs Y, Franz AR; ALBINO Study Group. BMC Pediatr. 2019 Jun 27;19(1):210. doi: 10.1186/s12887-019-1566-8

Non-invasive estimation of brain-volume in infants. Burkhardt W, Schneider D, Hahn G, Konstantelos D, Maas HG, Rüdiger M. Early Hum Dev. 2019 May;132:52-57. doi:10.1016/j.earlhumdev.2019.03.020

Impact of birthweight on health-care utilization during early childhood - a birth cohort study. Rüdiger M, Heinrich L, Arnold K, Druschke D, Reichert J, Schmitt J. BMC Pediatr. 2019 Mar 1;19(1):69. doi: 10.1186/s12887-019-1424-8

Oxygen Disrupts Human Fetal Lung Mesenchymal Cells. Implications for Bronchopulmonary Dysplasia. Möbius MA, Freund D, Vadivel A, Koss S, McConaghy S, Ohls RK, Rüdiger M, Thébaud B. Am J Respir Cell Mol Biol. 2019 May;60(5):592-600. doi: 10.1165/rcmb.2018-0358OC

Sniffin' Away the Feeding Tube: The Influence of Olfactory Stimulation on Oral Food Intake in Newborns and Premature Infants. Schriever VA, Gellrich J, Rochor N, Croy I, Cao-Van H, Rüdiger M, Hummel T. Chem Senses. 2018 Aug 24;43(7):469-474. doi: 10.1093/chemse/bjy034

"Crystal" and Pregnancy - The Preliminary Results of a Retrospective Study on the Course of Pregnancy and Delivery of Women Consuming Methamphetamine. Schmidt U, Capek C, Birdir C, Erfurt C, Nitzsche K. Z Geburtshilfe Neonatol. 2019 Aug;223(4):221-229. doi: 10.1055/a-0831-3642

Pregnancy and Wilson disease: management and outcome of mother and newborns-experiences of a perinatal centre. Reuner U, Dinger J.Reuner U, et al.  Ann Transl Med. 2019 Apr;7(Suppl 2):S56. doi: 10.21037/atm.2019.04.40.