Benutzerspezifische Werkzeuge


Clinicians and Scientists of the Saxonin Center for feto/neonatal Health do have a large international collaborative network. Results of the research collaboration have been published in various international journals. If you are interested to receive a PDF.file or to discuss published results, please do not hesitate to contact us.


A critical appraisal of tools for delivery room assessment of the newborn infant. Niemuth M, Küster H, Simma B, Rozycki H, Rüdiger M; European Society for Paediatric Research (ESPR) Neonatal Resuscitation Section Writing Group, Solevåg AL.Pediatr Res. 2021 Dec 30. doi: 10.1038/s41390-021-01896-7. Online ahead of print.

Functional morphometry to estimate the alveolar surface area by using a premature baboon model. Dassios T, Rüdiger M, McCurnin D, Seidner SR, Williams EE, Greenough A, Möbius MA.J Appl Physiol. 2021 Dec 9. doi: 10.1152/japplphysiol.00644.2021. Online ahead of print.

Video recording in the delivery room: current status, implications and implementation. Simma B, den Boer M, Nakstad B, Küster H, Herrick HM, Rüdiger M, Aichner H, Kaufmann M.Pediatr Res. 2021 Nov 24. doi: 10.1038/s41390-021-01865-0. Online ahead of print.

Systematic analysis of candidate reference genes for gene expression analysis in hyperoxia-based mouse models of bronchopulmonary dysplasia.Linge M, Möbius MA, Rösen-Wolff A, Winkler S.Am J Physiol Lung Cell Mol Physiol. 2021 Oct 1;321(4):L718-L725. doi: 10.1152/ajplung.00143.2021. Epub 2021 Aug 11.

Pharmacokinetic/Pharmacodynamic Modelling of Allopurinol, its Active Metabolite Oxypurinol, and Biomarkers Hypoxanthine, Xanthine and Uric Acid in Hypoxic-Ischemic Encephalopathy Neonates.Chu WY, Annink KV, Nijstad AL, Maiwald CA, Schroth M, Bakkali LE, van Bel F, Benders MJNL, van Weissenbruch MM, Hagen A, Franz AR, Dorlo TPC, Allegaert K, Huitema ADR; ALBINO Study Group.Clin Pharmacokinet. 2021 Oct 7. doi: 10.1007/s40262-021-01068-0. Online ahead of print

Course of the sFlt-1/PlGF ratio in fetal growth restriction and correlation with biometric measurements, feto-maternal Doppler parameters and time to delivery. Andrikos A, Andrikos D, Schmidt B, Birdir C, Kimmig R, Gellhaus A, Köninger A.Arch Gynecol Obstet. 2021 Aug 25. doi: 10.1007/s00404-021-06186-5. Online ahead of print.

Peripheral Arterial Lines in Extremely Preterm Neonates: A Potential Alternative to Umbilical Arterial Catheters. Mense L, Rose S, Bruck A, Rüdiger M, Kaufmann M, Seipolt B.Adv Neonatal Care. 2021 Jul 30. doi: 10.1097/ANC.0000000000000909. Online ahead of print

Anthropometric Landmark Detection in 3D Head Surfaces Using a Deep Learning Approach. Torres HR; Morais P; Fritze A; Oliveira B; Veloso F; Rüdiger M; Fonseca JC; Vilaca JL; IEEE J Biomed Health Inform. 2021 July, 25:7; doi: 10.1109/JBHI.2020.3035888

Are birth outcomes in low risk birth cohorts related to hospital birth volumes? A systematic review. Walther F, Kuester D, Bieber A, Malzahn J, Rüdiger M, Schmitt J.BMC Pregnancy Childbirth. 2021 Jul 27;21(1):531. doi: 10.1186/s12884-021-03988-y.

Neonatal outcome following maternal infection with SARS-CoV-2 in Germany: COVID-19-Related Obstetric and Neonatal Outcome Study (CRONOS). Mand N, Iannaccone A, Longardt AC, Hutten M, Mense L, Oppelt P, Maier RF, Pecks U, Rüdiger M; CRONOS Network; CRONOS-Network. Arch Dis Child Fetal Neonatal Ed. 2021 Jul 19:fetalneonatal-2021-322100. doi: 10.1136/archdischild-2021-322100. Online ahead of print.

Reference Charts for Neonatal Cranial Volume Based on 3D Laser Scanning to Monitor Head Growth. Vermeulen MJ, Burkhardt W, Fritze A, Roelants J, Mense L, Willemsen S, Rüdiger M.Front Pediatr. 2021 May 28;9:654112. doi: 10.3389/fped.2021.654112. eCollection 2021

Prenatal Methamphetamine Exposure: Effects on Child Development. Harst L, Deckert S, Haarig F, Reichert J, Dinger J, Hellmund P, Schmitt J, Rüdiger M.Dtsch Arztebl Int. 2021 May 7;118(18):313-319. doi: 10.3238/arztebl.m2021.0128.

Are two children at once better than one? Risk analysis of twin pregnancies and births after assisted reproduction.  Goeckenjan M, Madej D, Klimova A, Wimberger P, Birdir C, Glaß K.Eur J Obstet Gynecol Reprod Biol. 2021 Jul 4;264:76-82. doi: 10.1016/j.ejogrb.2021.06.047. Online ahead of print.

Reply letter to: Intubation in neonatal resuscitation - compelling necessity or incalculable risk? Roehr CC, Madar J, Morley CJ, Ainsworth S, Ersdal H, Rüdiger M, Skåre C, Szczapa T, Te Pas A, Trevisanuto D, Urlesberger B, Wilkinson D, Wyllie JP; ERC-NLS 2021 writing group.Resuscitation. 2021 Jun 2:S0300-9572(21)00206-9. doi: 10.1016/j.resuscitation.2021.05.022.

[Newborn resuscitation and support of transition of infants at birth].Madar J, Roehr CC, Ainsworth S, Ersda H, Morley C, Rüdiger M, Skåre C, Szczapa T, Te Pas A, Trevisanuto D, Urlesberger B, Wilkinson D, Wyllie JP.Notf Rett Med. 2021 Jun 2:1-47. doi: 10.1007/s10049-021-00894-w. Online ahead of print

Mother's Own Milk Feeding in Preterm Newborns Admitted to the Neonatal Intensive Care Unit or Special-Care Nursery: Obstacles, Interventions, Risk Calculation.Heller N, Rüdiger M, Hoffmeister V, Mense L.Int J Environ Res Public Health. 2021 Apr 14;18(8):4140. doi: 10.3390/ijerph18084140.

Auswirkungen von SARS-CoV-2 auf Schwangere und deren Neugeborene. Rüdiger M., Pecks U.  Connexiplus. 2021; 1; 48-55 

European Resuscitation Council Guidelines 2021: Newborn resuscitation and support of transition of infants at birth. Madar J, Roehr CC, Ainsworth S, Ersdal H, Morley C, Rüdiger M, Skåre C, Szczapa T, Te Pas A, Trevisanuto D, Urlesberger B, Wilkinson D, Wyllie JP. Resuscitation. 2021 Apr;161:291-326. doi: 10.1016/j.resuscitation.2021.02.014. Epub 2021 Mar 24.

Glomerular Filtration Rate in Asphyxiated Neonates Under Therapeutic Whole-Body Hypothermia, Quantified by Mannitol Clearance. Deferm N, Annink KV, Faelens R, Schroth M, Maiwald CA, Bakkali LE, van Bel F, Benders MJNL, van Weissenbruch MM, Hagen A, Smits A, Annaert P, Franz AR, Allegaert K; ALBINO Study Group.Clin Pharmacokinet. 2021 Feb 21. doi: 10.1007/s40262-021-00991-6. Online ahead of print.

[Association between Socioeconomic Status and Developmental Status: Data Linkage of Results of the Daycare and School Entry Health Examinations of a Saxon Birth Cohort Study]. Redemann D, Arnold K, Druschke D, Heinrich L, Rüdiger M, Reichert J, Schmitt J.Gesundheitswesen. 2021 Jan 25. doi: 10.1055/a-1327-2463. Online ahead of print

Roland R. Wauer (1942-2020): neonatologist, scientist, teacher and visionary. Rüdiger M, Reichert J, Proquitte H, Schmalisch G, Hammer H, Weigel H, Wilitzki S, Fentsch P, Roehr CC.Pediatr Res. 2021 Jan 14. doi: 10.1038/s41390-020-01338-w. Online ahead of print.

Obstetric forceps dimensions and the newborn head biometry: Time for an update. Ismail AT, Fritze A, Rüdiger M,  Isamil KMEur J Obstet Gynecol Reprod Biol. 2021 Jan;256:270-273. doi: 10.1016/j.ejogrb.2020.11.046.


Pregnancy and SARS-CoV-2 Infection in Germany-the CRONOS Registry.   Pecks U, Kuschel B, Mense L, Oppelt P, Rüdiger M; CRONOS Network.PecDtsch Arztebl Int. 2020 Dec 4;117(49):841-842. doi: 10.3238/arztebl.2020.0841.

Placenta accreta spectrum disorders-experience of management in a German tertiary perinatal centre. Bluth A, Schindelhauer A, Nitzsche K, Wimberger P, Birdir C. Arch Gynecol Obstet. 2020 Dec 7. doi: 10.1007/s00404-020-05875-x. Online ahead of print.

Evaluation of carcinoembryonic antigen-related cell adhesion molecule 1 blood serum levels in women at high risk for preeclampsia.  Mach P, Andrikos D, Schmidt B, Gellhaus A, Rusch P, Birdir C, Andrikos A, Schmitt V, Kimmig R, Singer BB, Köninger A.Am J Reprod Immunol. 2020 Nov 11:e13375. doi: 10.1111/aji.13375. Online ahead of print.

Results of the hypothermia registry of the University Hospital Dresden from 2010-2017. Application of hypothermia therapy in newborns in Germany. Scherer J, Whybra-Trümpler C, Mildenberger E Z Geburtshilfe Neonatol. 2020 Dec;224(6):367-373. doi: 10.1055/a-1164-7174.   

CRONOS-Netzwerk: Pregnancy and SARS CoV-2 infection in Germany - the CRONOS registry. Peck U, Kuschel B, Mense L, Oppelt P, Rüdiger M. Dtsch Arztebl Int 2020;117: 841-2. DOI: 10.3238/ arztebl.2020.0841

Anthropometric Landmark Detection in 3D Head Surfaces using a Deep Learning Approach. Torres HR; Morais P; Fritze A; Oliveira B; Veloso F; Rüdiger M; Fonseca JC; Vilaca JL; IEEE J Biomed Health Inform. 2020 Nov 4;PP. doi: 10.1109/JBHI.2020.3035888. Online ahead of print.PMID: 33147152

Neonatal Life Support: 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Wyckoff MH, Wyllie J, Aziz K, de Almeida MF, Fabres J, Fawke J, Guinsburg R, Hosono S, Isayama T, Kapadia VS, Kim HS, Liley HG, McKinlay CJD, Mildenhall L, Perlman JM, Rabi Y, Roehr CC, Schmölzer GM, Szyld E, Trevisanuto D, Velaphi S, Weiner GM; Neonatal Life Support Collaborators.Wyckoff MH, et al. Circulation. 2020 Oct 20;142(16_suppl_1):S185-S221. doi: 10.1161/CIR.0000000000000895.

Neonatal Life Support 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Wyckoff MH, Wyllie J, Aziz K, de Almeida MF, Fabres JW, Fawke J, Guinsburg R, Hosono S, Isayama T, Kapadia VS, Kim HS, Liley HG, McKinlay CJD, Mildenhall L, Perlman JM, Rabi Y, Roehr CC, Schmölzer GM, Szyld E, Trevisanuto D, Velaphi S, Weiner GM; Neonatal Life Support Collaborators.Resuscitation. 2020 Nov;156:A156-A187. doi: 10.1016/j.resuscitation.2020.09.015.

Impact of regionalisation and case-volume on neonatal and perinatal mortality: an umbrella review. Walther F, Küster DB, Bieber A, Rüdiger M, Malzahn J, Schmitt J, Deckert S. BMJ Open. 2020 Sep 25;10(9):e037135. doi: 10.1136/bmjopen-2020-037135

Apgar Score-It Is Time to Avoid Pain-Reply. Rüdiger M, Rozycki HJ JAMA Pediatr. 2020 Sep 14. doi: 10.1001/jamapediatrics.2020.2560. 

Effects of Liberal vs Restrictive Transfusion Thresholds on Survival and Neurocognitive Outcomes in Extremely Low-Birth-Weight Infants: The ETTNO Randomized Clinical Trail. Franz AR, Engel C, Bassler D, Rüdiger M, Thome UH, Maier RF, Krägeloh-Mann I, Kron M, Essers J, Bührer C, Rellensmann G, Rossi R, Bittrich HJ, Roll C, Höhn T, Ehrhardt H, Avenarius S, Körner HT, Stein A, Buxmann H, Vochem M, Poets CF; ETTNO Investigators. JAMA. 2020 Aug 11;324(6):560-570. doi: 10.1001/jama.2020.10690

MR-proANP, a cardiovascular biomarker to predict late-onset preeclampsia and intrauterine growth restricted fetuses. Birdir C, Fox L, Droste L, Frank M, Fryze J, Enekwe A, Köninger A, Kimmig R, Schmidt B, Gellhaus A. Pregnancy Hypertens. 2020 Jul 13;22:54-58. doi: 10.1016/j.preghy.2020.07.004. 

Prenatal Prediction of Outcome by Fetal Gasteoschisis in a Tertiary Referral Center. Nitzsche K, Fitze G, Rüdiger M, Birdir C.Diagnostics (Basel). 2020 Jul 30;10(8):540. doi: 10.3390/diagnostics10080540

Newborn care and life support. Madar J, Roehr C, Ainsworth S, Ersdal H, Morley C, Rüdiger M, Skåre C, Szczapa T, Te Pas A, Trevisanuto D, Urlesberger B, Wilkinson D, Wyllie J.Notf Rett Med. 2020;23(4):257-259. doi: 10.1007/s10049-020-00722-7

European Resuscitation Council COVID-19 guidelines executive summary. Nolan JP, Monsieurs KG, Bossaert L, Böttiger BW, Greif R, Lott C, Madar J, Olasveengen TM, Roehr CC, Semeraro F, Soar J, Van de Voorde P, Zideman DA, Perkins GD; European Resuscitation Council COVID-Guideline Writing Groups. Resuscitation. 2020 Aug;153:45-55. doi: 10.1016/j.resuscitation.2020.06.001

Neonatal and young infant sepsis by Group B Streptococci and Escherichia coli: a single-center retrospective analysis in Germany-GBS screening implementation gaps and reduction in antibiotic resistance. Doenhardt M, Seipolt B, Mense L, Winkler JL, Thürmer A, Rüdiger M, Berner R, Armann J. Eur J Pediatr. 2020 Nov;179(11):1769-1777. doi: 10.1007/s00431-020-03659-8. Epub 2020 May 23

Delivery Room Management of Infants with Very Low Birth Weight in 3 European Countries - Theo Video Study. Simma B, Walter S, Konstantelos D, van Vonderen J, Te Pas AB, Rüdiger M, Küster H. J Pediatr. 2020 Jul;222:106-111.e2. doi: 10.1016/j.jpeds.2020.03.035. Epub 2020 May 14

Individual-Level Linkage of Primary and Secondary Data from Three Sources for Comprehensive Analyses of Low Birthweight Effects. Druschke D, Arnold K, Heinrich L, Reichert J, Rüdiger M, Schmitt J. Gesundheitswesen. 2020 Mar;82(S 02):S108-S116. doi: 10.1055/a-1082-0740. Epub 2020 Mar 19

It`s Time to Reevaluate the Apgar Score. Rüdiger M, Rozycki HJ. JAMA Pediatr. 2020 Apr 1;174(4):321-322. doi: 10.1001/jamapediatrics.2019.6016

Surgical necrotizing enterocolitis but not spontaneous intestinal perforation is associated with adverse neurological outcome at school age. Humberg A, Spiegler J, Fortmann MI, Zemlin M, Marissen J, Swoboda I, Rausch TK, Herting E, Göpel W, Härtel C; German Neonatal Network (GNN). Sci Rep. 2020 Feb 11;10(1):2373. doi: 10.1038/s41598-020-58761-6

How to introduce MSC-based therapy for the developing lung safely into clinical care? Rüdiger M, Kirpalani H, Steinhorn R, Davis JM, Thebaud B. Pediatr Res. 2020 Sep;88(3):365-368. doi: 10.1038/s41390-020-0758-0

Intrauterine Growth Restriction: Transsectoral, Interdisciplinary and Multiprofessional Care for Pregnant Women and Newborns in a Feto-neonatal Pathway: A project of the Innovationsfonds. Mense L, Birdir C, Reichert J, Schleußner E, Proquitté H, Schmitt J, Müller G, Rüdiger M. Z Geburtshilfe Neonatol. 2020 Feb;224(1):15-21. doi: 10.1055/a-0998-4532

Hospital survey showed wide variations in therapeutic hypothermia for neonates in Germany. Giannakis S, Ruhfus M, Rüdiger M, Sabir H; German Neonatal Hypothermia Network. Acta Paediatr. 2020 Jan;109(1):200-201. doi: 10.1111/apa.14979

Late Rescue Therapy with Cord-Derived Mesenchymal Stromal Cells for Established Lung Injury in Experimental Bronchopulmonary Dysplasia. O'Reilly M, Möbius MA, Vadivel A, Ionescu L, Fung M, Eaton F, Greer JJ, Thébaud B. Stem Cells Dev. 2020 Mar 15;29(6):364-371. doi: 10.1089/scd.2019.0116


Effect of allopurinol in addition to hypothermia treatment in neonates for hypoxic-ischemic brain injury on neurocognitive outcome (ALBINO): study protocol of a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III). Maiwald CA, Annink KV, Rüdiger M, Benders MJNL, van Bel F, Allegaert K, Naulaers G, Bassler D, Klebermaß-Schrehof K, Vento M, Guimarães H, Stiris T, Cattarossi L, Metsäranta M, Vanhatalo S, Mazela J, Metsvaht T, Jacobs Y, Franz AR; ALBINO Study Group. BMC Pediatr. 2019 Jun 27;19(1):210. doi: 10.1186/s12887-019-1566-8

Non-invasive estimation of brain-volume in infants. Burkhardt W, Schneider D, Hahn G, Konstantelos D, Maas HG, Rüdiger M. Early Hum Dev. 2019 May;132:52-57. doi:10.1016/j.earlhumdev.2019.03.020

Impact of birthweight on health-care utilization during early childhood - a birth cohort study. Rüdiger M, Heinrich L, Arnold K, Druschke D, Reichert J, Schmitt J. BMC Pediatr. 2019 Mar 1;19(1):69. doi: 10.1186/s12887-019-1424-8

Oxygen Disrupts Human Fetal Lung Mesenchymal Cells. Implications for Bronchopulmonary Dysplasia. Möbius MA, Freund D, Vadivel A, Koss S, McConaghy S, Ohls RK, Rüdiger M, Thébaud B. Am J Respir Cell Mol Biol. 2019 May;60(5):592-600. doi: 10.1165/rcmb.2018-0358OC

Sniffin' Away the Feeding Tube: The Influence of Olfactory Stimulation on Oral Food Intake in Newborns and Premature Infants. Schriever VA, Gellrich J, Rochor N, Croy I, Cao-Van H, Rüdiger M, Hummel T. Chem Senses. 2018 Aug 24;43(7):469-474. doi: 10.1093/chemse/bjy034

"Crystal" and Pregnancy - The Preliminary Results of a Retrospective Study on the Course of Pregnancy and Delivery of Women Consuming Methamphetamine. Schmidt U, Capek C, Birdir C, Erfurt C, Nitzsche K. Z Geburtshilfe Neonatol. 2019 Aug;223(4):221-229. doi: 10.1055/a-0831-3642

Pregnancy and Wilson disease: management and outcome of mother and newborns-experiences of a perinatal centre. Reuner U, Dinger J.Reuner U, et al.  Ann Transl Med. 2019 Apr;7(Suppl 2):S56. doi: 10.21037/atm.2019.04.40.