Feto/neonatal Transition

Optimizing the golden hour of life by improving management in the Delivery Room (DR). Feto-neonatal transition represents a crucial event which determines long term health. Therefore, research focuses on improving management in DR. In particular, video-analysis is used to evaluate current management. Furthermore, new scores, such as the Combined-Apgar, are developed and evaluated in order to improve DR-management. Results of the research are implemented into International Resuscitation guidelines. Currently, the impact of physiology based cord clamping on postnatal adaptation is studied together with collaborators in Netherlands. Furthermore, an adapted scoring system is developed which better describes the clinical status and the intervention that are needed to achieve this condition.

Group

Team_transition

Lars Mense, Maxi Kaufmann, Barbara Seipolt

News

First babies have been treated with the Concord-Birth troley. As the first center in Germany the Concord Birth troley was used in several newborns. It is a great progress toward new strategy in treating extremly preterm infants. Find a news report here.

Research results are presented at the PAS-meeting. Maxi Kaufmann presents her research results on video analysis of delivery room management during the annual meeting of the American Academic Societies (PAS), which takes place as an online event. Another presentation is given by Lars Mense, he presents data on the Dresden approach of surfactant administration in the delivery room.

Collaborations

Arjan te Pas; University Leiden (UL), Netherlands;

Charles Christoph Roehr, University Oxford (UO), Great Britain;

Liz Foglia and Heidi Herricks; Childrens Hosital of Philadelphia (CHOP), USA;

Henry Rozycki, Children´s Hospital of Richmond at VCU, Richmond (CHR), USA

Current Doctoral Students

Selected Publications

European Resuscitation Council Guidelines 2021: Newborn resuscitation and support of transition of infants at birth. Madar J, Roehr CC, Ainsworth S, Ersdal H, Morley C, Rüdiger M, Skåre C, Szczapa T, Te Pas A, Trevisanuto D, Urlesberger B, Wilkinson D, Wyllie JP. Resuscitation. 2021 Apr;161:291-326. doi: 10.1016/j.resuscitation.2021.02.014. Epub 2021 Mar 24.

Neonatal Life Support: 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Wyckoff MH, et al. Circulation. 2020 Oct 20;142(16_suppl_1):S185-S221.

European Resuscitation Council COVID-19 guidelines executive summary. European Resuscitation Council COVID-Guideline Writing Groups. Resuscitation. 2020 Aug;153:45-55.

Delivery Room Management of Infants with Very Low Birth Weight in 3 European Countries - The Video Apgar Study. Simma B, et al. J Pediatr. 2020 Jul;222:106-111.e2. doi: 10.1016/j.jpeds.2020.03.035. Epub 2020 May 14

It`s Time to Reevaluate the Apgar Score. Rüdiger M, et al. JAMA Pediatr. 2020 Apr 1;174(4):321-322. doi: 10.1001/jamapediatrics.2019.6016

Resuscitating neonates: 65 years after Virginia Apgar. Rüdiger M. BMJ Paediatr Open. 2017 Nov 9;1(1):e000195. doi: 10.1136/bmjpo-2017-000195. eCollection 2017

Analyzing video recorded support of postnatal transition in preterm infants following a c-section. Konstantelos D, et al. BMC Pregnancy Childbirth. 2016 Aug 25;16(1):246. doi: 10.1186/s12884-016-1045-2

European Resuscitation Council Guidelines for Resuscitation 2015: Section 7. Resuscitation and support of transition of babies at birth. Wyllie J, et al. Resuscitation. 2015 Oct;95:249-63. doi: 10.1016/j.resuscitation.2015.07.029. Epub 2015 Oct 15

Neonatal assessment in the delivery room -- Trial to Evaluate a Specified Type of Apgar (TEST-Apgar). Rüdiger M, et al. BMC Pediatr. 2015 Mar 8;15:18. doi: 10.1186/s12887-015-0334-7

Mask CPAP during neonatal transition: too much of a good thing for some term infants? Poets CF, Rüdiger M. Arch Dis Child Fetal Neonatal Ed. 2015 Sep;100(5):F378-9. doi: 10.1136/archdischild-2015-308236. Epub 2015 Apr 15

Apgar score and risk of cause-specific infant mortality. Rüdiger M, et al. Lancet. 2015 Feb 7;385(9967):505-6. doi: 10.1016/S0140-6736(15)60196-9

Suctioning habits in the delivery room and the influence on postnatal adaptation - a video analysis. Konstantelos D, et al. J Perinat Med. 2015 Nov;43(6):777-82. doi: 10.1515/jpm-2014-0188