Immunotherapy and Cancer Immunology

Prof. Dr. rer. nat. et med. habil. Michael Bachmann (CV)

Research Topics:

1. Activation of immune effector cells against tumor cells with recombinant antibody derivatives
2. Identification of specific or inducible immunotargets on tumor cells
3. Radio- or chemotherapy-induced expression of target molecules for specific tumor immunotherapy

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Dr. Marc Cartellieri, Post-Doc (CV)

Research Topics:

1. Tumour immunotherapy
2. Tumour immunology
3. T and NK cell biology

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Prof. Dr. Gerhard Ehninger (CV)

Research Topics:

-    Leukemia, stem cell biology and haematopoietic blood stem cell transplantation

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Karsten Kretschmer, PhD (CV)

Research Topics:

1. Molecular and cellular pathways governing the generation and function of Treg cells
2. Mechanisms of immune regulation by Foxp3- and Foxp3+ Treg cells
3. Molecular networks in immunity, tolerance and autoimmunity (including miRNAs)
4. Antigen-specific Treg cells as gain-of-function targets in autoimmunity and transplantation
5. Role of Treg in homeostatic hematopoiesis and hematopoietic stem cell transplantation
6. Neuro-immune crosstalk in health and disease

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Prof. Dr. med. Uwe Platzbecker (CV)

Research Topics:

1. Microenvironment and transplantation immunology
2. Targeted therapies

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Prof. Dr. med. Axel Roers (CV)

Research Topics:

1. Role of mast cells in tumor biology
2. Inhibition of anti-tumor immunity by IL-10 derived from different cellular sources

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PD Dr. Johannes Schetelig (CV)

Research Topics:

-    Clinical development of allogeneic immunotherapy

Prof. Dr. med. Marc Schmitz (CV)

Research Topics:

1. Identification of tumor-associated antigens for specific immunotherapy of tumors
2. Modulation of the immunostimulatory properties of native human dendritic cells by tumor cells

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Prof. Dr. rer. nat. Hanns Achim Temme (CV)

Research Topics:

1. Identification and characterization of glioma associated antigens and use thereof in experimental immunotherapy and gene therapy approaches
2. Role of Chromosomal Passenger Proteins in apoptosis, proliferation and migration of tumor cells

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