Key Publications

Keck B, Wach S, Taubert H, Zeiler S, Ott OJ, Kunath F, Hartmann A, Bertz S, Weiss C, Hönscheid P, Schellenburg S, Rödel C, Baretton GB, Sauer R, Fietkau R, Wullich B, Krause FS, Datta K, Muders MH. (2014) Neuropilin-2 and its ligand VEGF-C predict treatment response after transurethral resection and radiochemotherapy in bladder cancer patients. Int J Cancer, May 27.

Chatzigeorgiou A, Chung KJ, Garcia-Martin R, Alexaki VI, Klotzsche-von Ameln A, Phieler J, Sprott D, Kanczkowski W, Tzanavari T, Bdeir M, Bergmann S, Cartellieri M, Bachmann M, Nikolakopoulou P, Androutsellis-Theotokis A, Siegert G, Bornstein SR, Muders MH, Boon L, Karalis KP, Lutgens E, Chavakis T. (2014) Dual role of B7 costimulation in obesity-related non-alcoholic steatohepatitis (NASH) and metabolic dysregulation. Hepatology May 21.

Thieme S, Gyárfás T, Richter C, Özhan G, Fu J, Alexopoulou D, Muders MH, Michalk I, Jakob C, Dahl A, Klink B, Bandola J, Bachmann M, Schröck E, Buchholz F, Stewart AF, Weidinger G, Anastassiadis K, Brenner S. (2013) The histone demethylase UTX regulates stem cell migration and hematopoiesis. Blood. 121(13):2462-73.

Stanton MJ, Dutta S, Zhang H, Polavaram NS, Leontovich AA, Hönscheid P, Sinicrope FA, Tindall DJ, Muders MH*, Datta K*. (2013) Autophagy control by the VEGF-C/NRP-2 axis in cancer and its implication for treatment resistance. Cancer Res. Jan 1;73(1):160-71. *equal contribution as corresponding and senior author.

Franke K, Kalucka J, Mamlouk S, Singh RP, Muschter A, Weidemann A, Iyengar V, Jahn S, Wieczorek K, Geiger K, Muders M, Sykes AM, Poitz DM, Ripich T, Otto T, Bergmann S, Breier G, Baretton G, Fong GH, Greaves DR, Bornstein S, Chavakis T, Fandrey J, Gassmann M, Wielockx B. (2013) HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis. Blood. 2013 21;121(8):1436-45.

Jakob C, Aust DE, Liebscher B, Baretton GB, Datta K, Muders MH. (2011) Lymphangiogenesis in Regional Lymph Nodes is an Independent Prognostic Marker in Rectal Cancer Patients after Neoadjuvant Treatment. PLoS One. 2011;6(11):e27402.

Rowley M, Ohashi A, Mondal G, Mills L, Yang L, Zhang L, Sundsbak R, Shapiro V, Muders MH, Smyrk T, Couch FJ.(2011) Inactivation of Brca2 promotes Trp53-associated but inhibits KrasG12D dependent pancreatic cancer development in mice. Gastroenterology. 140(4):1303-1313.

Fu Z., Regan K., Zhang L., Muders MH, Thibodeau SN, French A, Wu Y, Kaufmann SH, Lingle WL, Chen J, Tindall DJ.(2009) Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibilty in mice. J Clin Invest. 119(9):2714-24.

Muders MH, Zhang H, Wang E, Tindall DJ, Datta K. (2009) Vascular endothelial growth factor-C protects prostate cancer cells from oxidative stress by the activation of mammalian target of rapamycin complex-2 and Akt-1. Cancer Res. 69(15):6042-48

Muders MH, Vohra PK, Dutta SK, Wang E, Ikeda Y, Wang L, Udugamasooriya DG, Memic A, Rupasinge CN, Baretton GB, Aust DE, Langer S, Datta K, Simons M, Spaller MR, Mukhopadhyay D (2009), Targeting GIPC/Synectin in pancreatic cancer inhibits tumor growth. Clin Cancer Res 15(12): 4095-103

Zhang H, Muders MH, Li J, Rindaldo F, Tindall DJ, Datta K (2008). Loss of NKX3.1 favors vascular endothelial growth factor-C expression in prostata cancer. Cancer Res. 68 (21):8770-8.

Rinaldo F, Li J, Wang E, Muders M, Datta K. (2007) RalA regulates vascular endothelial growth factor-C (VEGF-C) synthesis in prostate cancer cells during androgen ablation. Oncogene 26(12):1731-8.

Muders MH, Dutta SK, Wang L, Lau JS, Bhattacharya R, Smyrk TC, Chari ST, Datta K, Mukhopadhyay D. (2006) Expression and regulatory role of GAIP-interacting protein GIPC in pancreatic adenocarcinoma. Cancer Res 66(21): 10264-8.

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