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2015

1.            Sipos B, Sperveslage J, Anlauf M, Hoffmeister M, Henopp T, Buch S, Hampe J, Weber A, Hammel P, Couvelard A, Höbling W, Lieb W, Boehm BO, Klöppel G. Glucagon cell hyperplasia and neoplasia with and without glucagon receptor mutations. J Clin Endocr Metab. 2015;100(5):E783-8. (IF 6,2)

2.            Müller N, Schulte DM, Türk K, Freitag-Wolf S, Hampe J, Zeuner R, Schröder JO, Gouni-Berthold I, Berthold HK, Krone W, Rose-John S, Schreiber S, Laudes M. IL-6 blockade by monoclonal antibodies inhibits apolipoprotein (a) expression and lipoprotein (a) synthesis in humans. J Lipid Res. 2015;56(5):1034-42. (IF 4,4)

3.            Milano M, Aghemo A, Mancina RM, Fischer J, Dongiovanni P, De Nicola S, Fracanzani AL, D'Ambrosio R, Maggioni M, De Francesco R, Fargion S, Berg T, Stickel F, Hampe J, Romeo S, Colombo M, Valenti L. Transmembrane 6 superfamily member 2 gene E167K variant impacts on steatosis and liver damage in chronic hepatitis C patients. Hepatology. 2015;62(1):111-7. (IF 11,0)

4.            Patsenker E, Sachse P, Chicca A, Gachet MS, Schneider V, Mattsson J, Lanz C, Worni M, de Gottardi A, Semmo M, Hampe J, Schafmayer C, Brenneisen R, Gertsch J, Stickel F, Semmo N. Elevated levels of endocannabinoids in chronic hepatitis C may modulate cellular immune response and hepatic stellate cell activation. Int J Mol Sci. 2015;16(4):7057-76. (IF 2,8)

5.            Brückner S, Arlt A, Hampe J. Endoscopic ultrasound-guided biliary drainage using a lumen-apposing self-expanding metal stent: a case series. Endoscopy. 2015 epub (IF 5,0)

6.            Chambers JC, Loh M, Lehne B, Drong A, Kriebel J, Motta V, Wahl S, Elliott HR, Rota F, Scott WR, Zhang W, Tan ST, Campanella G, Chadeau-Hyam M, Yengo L, Richmond RC, Adamowicz-Brice M, Afzal U, Bozaoglu K, Mok ZY, Ng HK, Pattou F, Prokisch H, Rozario MA, Tarantini L, Abbott J, Ala-Korpela M, Albetti B, Ammerpohl O, Bertazzi PA, Blancher C, Caiazzo R, Danesh J, Gaunt TR, de Lusignan S, Gieger C, Illig T, Jha S, Jones S, Jowett J, Kangas AJ, Kasturiratne A, Kato N, Kotea N, Kowlessur S, Pitkäniemi J, Punjabi P, Saleheen D, Schafmayer C, Soininen P, Tai ES, Thorand B, Tuomilehto J, Wickremasinghe AR, Kyrtopoulos SA, Aitman TJ, Herder C, Hampe J, Cauchi S, Relton CL, Froguel P, Soong R, Vineis P, Jarvelin MR, Scott J, Grallert H, Bollati V, Elliott P, McCarthy MI, Kooner JS. Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study. Lancet Diabetes Endo 2015;3(7):526-34. (IF 9,1)

7.            Buch S, Stickel S, Trépo E, … Moreno C, Franchimont D, Morgan MY, Hampe J. A two-stage genome-wide association study identifies TM6SF2 and MBOAT7 as novel risk loci for alcohol-relatived liver cirrhosis. Nat Genet 2015, epub. (IF 29,3)

2014

  1. Schlesinger S, Walter J, Hampe J, von Schönfels W, Hinz S, Küchler T, Jacobs G, Schafmayer C, Nöthlings U. Lifestyle factors and health-related quality of life in colorectal cancer survivors. Cancer Control. 2014;25(1):99-110 (IF 3,5)
  2. Yang R, Chen B, Pfütze K, Buch S, Steinke V, Holinski-Feder E, Stöcker S, von Schönfels W, Becker T, Schackert HK, Royer-Pokora B, Kloor M, Schmiegel WH, Büttner R, Engel C, Lascorz Puertolas J, Försti A, Kunkel N, Bugert P, Schreiber S, Krawczak M, Schafmayer C, Propping P, Hampe J, Hemminki K, Burwinkel B. Genome-wide analysis associates familial colorectal cancer with increases in copy number variations and a rare structural variation at 12p12.3. Carcinogenesis. 2014;35:315-23 (IF 5,3)
  3. Heits N, Stapel L, Reichert B, Schafmayer C, Schniewind B, Becker T, Hampe J, Egberts JH. Endoscopic endoluminal vacuum therapy in esophageal perforation. Ann Thorac Surg. 2014;97:1029-35 (IF 3,8)
  4. von Schönfels W, Patsenker E, Fahrner R, Itzel T, Hinrichsen H, Brosch M, Erhart W, Gruodyte A, Vollnberg B, Richter K, Landrock A, Schreiber S, Brückner S, Beldi G, Sipos B, Becker T, Röcken C, Teufel A, Stickel F, Schafmayer C, Hampe J. Metabolomic tissue signature in human non-alcoholic fatty liver disease identifies protective candidate metabolites. Liver Int. 2014;. Epub (IF 4,8)
  5. Stickel F, Buch S, Zoller H, Hultcrantz R, Gallati S, Osterreicher C, Finkenstedt A, Stadlmayr A, Aigner E, Sahinbegovic E, Sarrazin C, Schafmayer C, Braun F, Erhart W, Nothnagel M, Lerch MM, Mayerle J, Völzke H, Schaller A, Kratzer W, Boehm BO, Sipos B, D'Amato M, Torkvist L, Stal P, Arlt A, Franke A, Becker T, Krawczak M, Zwerina J, Berg T, Hinrichsen H, Krones E, Dejaco C, Strasser M, Datz C, Hampe J. Evaluation of genome-wide loci of iron metabolism in hereditary hemochromatosis identifies PCSK7 as a host risk factor of liver cirrhosis. Hum Mol Genet. 2014. Epub (IF 6,3)
  6. Müller N, Schulte DM, Hillebrand S, Türk K, Hampe J, Schafmayer C, Brosch M, von Schönfels W, Ahrens M, Zeuner R, Schröder JO, Blüher M, Gutschow C, Freitag-Wolf S, Stelmach-Mardas M, Saggau C, Schreiber S, Laudes M. B Lymphocyte Stimulator (BLyS) Is Expressed in Human Adipocytes In Vivo and Is Related to Obesity but Not to Insulin Resistance. PLoS One. 2014;9:e94282 (IF 3,2)
  7. Schmelz R, Bornhäuser M, Schetelig J, Kiani A, Platzbecker U, Schwanebeck U, Grählert X, Uharek L, Aust D, Baretton G, Schwerdtfeger R, Hampe J, Greinwald R, Mueller R, Ehninger G, Miehlke S. Randomised, double-blind, placebo-controlled trial of oral budesonide for prophylaxis of acute intestinal graft-versus-host disease after allogeneic stem cell transplantation (PROGAST). BMC Gastroenterol. 2014;14(1):197 (IF 2,3)
  8. Horvath S, Erhart W, Brosch M, Ammerpohl O, von Schönfels W, Ahrens M, Heits N, Bell JT, Tsai PC, Spector TD, Deloukas P, Siebert R, Sipos B, Becker T, Röcken C, Schafmayer C, Hampe J. Obesity accelerates epigenetic aging of human liver. P Natl Acad Sci USA  2014;111(43):15538-43 (IF 9,6)
  9. Schlesinger S, Siegert S, Koch M, Walter J, Heits N, Hinz S, Jacobs G, Hampe J, Schafmayer C, Nöthlings U. Postdiagnosis body mass index and risk of mortality in colorectal cancer survivors: a prospective study and meta-analysis. Cancer Control. 2014;25(10):1407-18. (IF 3,5)
  10. Walter D, Will U, Sanchez-Yague A, Brenke D, Hampe J, Wollny H, López-Jamar JM, Jechart G, Vilmann P, Gornals JB, Ullrich S, Fähndrich M, de Tejada AH, Junquera F, Gonzalez-Huix F, Siersema PD, Vleggaar FP. A novel lumen-apposing metal stent for endoscopic ultrasound-guided drainage of pancreatic fluid collections: a prospective cohort study. Endoscopy. 2014;47(1):63-7 (IF 5,0)
  11. Derikx MH, Kovacs P, Scholz M, Masson E, Chen JM, Ruffert C, Lichtner P, Te Morsche RH, Cavestro GM, Algül H, Berg T, Bödeker H, Blüher M, Bruno MJ, Buch S, Bugert P, Cichoz-Lach H, Dabrowski A, Farré A, Frank J, Gasiorowska A, Geisz A, Goni E, Grothaus J, Grützmann R, Haas S, Hampe J, Hellerbrand C, Hegyi P, Huster D, Ioana M, Iordache S, Jurkowska G, Keim V, Landt O, Di Leo M, Lerch MM, Lévy P, Löhr MJ, Macek M, Malats N, Malecka-Panas E, Mariani A, Martorana D, Mayerle J, Mora J, Mössner J, Müller S, Ockenga J, Paderova J, Pedrazzoli S, Pereira SP, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rohde K, Sack S, Saftoiu A, Schneider A, Schulz HU, Soyka M, Simon P, Skipworth J, Stickel F, Stumvoll M, Testoni PA, Tönjes A, Treiber M, Weiss FU, Werner J, Wodarz N, Férec C, Drenth JP, Witt H, Rosendahl J. Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study. Gut. 2014 Sep 24. (IF 14,6)
  12. Hauser C, Patett C, von Schoenfels W, Heits N, Schafmayer C, Malchow B, Hampe J, Schniewind B, Becker T, Egberts JH. Does neoadjuvant treatment before oncologic esophagectomy affect the postoperative quality of life? A prospective, longitudinal outcome study.  Dis Esophagus. 2014 Jul 25. doi: 10.1111/dote.12257. (IF 1,7)
  13. Stickel F, Buch S, Zoller H, Hultcrantz R, Gallati S, Österreicher C, Finkenstedt A, Stadlmayr A, Aigner E, Sahinbegovic E, Sarrazin C, Schafmayer C, Braun F, Erhart W, Nothnagel M, Lerch MM, Mayerle J, Völzke H, Schaller A, Kratzer W, Boehm BO, Sipos B, D'Amato M, Torkvist L, Stal P, Arlt A, Franke A, Becker T, Krawczak M, Zwerina J, Berg T, Hinrichsen H, Krones E, Dejaco C, Strasser M, Datz C, Hampe J,  Evaluation of genome-wide loci of iron metabolism in hereditary hemochromatosis identifies PCSK7 as a host risk factor of liver cirrhosis. Hum Genet. 2014;23(14):3883-90. (IF 4,8)
  14. Kinnersley B, Buch S, Castellví-Bel S, Farrington SM, Forsti A, Hampe J, Hemminki K, Hofstra RM, Northwood E, Palles C, Pinheiro M, Ruiz-Ponte C, Schafmayer C, Teixeira MR, Westers H, Wezel Tv, Bishop DT, Tomlinson I, Dunlop MG, Houlston RS. Re: Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis. J Natl Cancer Inst. 2014;106(5). (IF 12,5)
  15. Heits N, Stapel L, Reichert B, Schafmayer C, Schniewind B, Becker T, Hampe J, Egberts JH. Endoscopic endoluminal vacuum therapy in esophageal perforation. Ann Thorac Surg 2014 Mar;97(3):1029-35. IF 3,8)
  16. Yang R, Chen B, Pfütze K, Buch S, Steinke V, Holinski-Feder E, Stöcker S, von Schönfels W, Becker T, Schackert HK, Royer-Pokora B, Kloor M, Schmiegel WH, Büttner R, Engel C, Lascorz Puertolas J, Försti A, Kunkel N, Bugert P, Schreiber S, Krawczak M, Schafmayer C, Propping P, Hampe J, Hemminki K, Burwinkel B. Genome-wide analysis associates familial colorectal cancer with increases in copy number variations and a rare structural variation at 12p12.3 Carcinogenesis. 2014 Feb;35(2):315-23. (IF 5,3)
  17. von Schönfels W, Patsenker E, Fahrner R, Itzel T, Hinrichsen H, Brosch M, Erhart W, Gruodyte A, Vollnberg B, Richter K, Landrock A, Schreiber S, Brückner S, Beldi G, Sipos B, Becker T, Röcken C, Teufel A, Stickel F, Schafmayer C, Hampe J. Metabolomic tissue signature in human non-alcoholic fatty liver disease identifies protective candidate metabolites.  Liver Int. 2014 Feb 1. 24484068. (IF 4,8)
  18. Schlesinger S, Walter J, Hampe J, von Schönfels W, Hinz S, Küchler T, Jacobs G, Schafmayer C, Nöthlings U. Lifestyle factors and health-related quality of life in colorectal cancer survivors.  Cancer Control. 2014 Jan;25(1):99-110. 24158780. (IF 3,5)
  19. Szafranski K, Fritsch C, Schumann F, Siebel L, Sinha R, Hampe J, Hiller M, Englert C, Huse K, Platzer M.  Physiological state co-regulates thousands of mammalian mRNA splicing events at tandem splice sites and alternative exons.  Nucleic Acids Res. 2014;42(14):8895-904. 10.1093/nar/gku 53225030907. (IF 9.1)
  20. Abulí A, Bujanda L, Muñoz J, Buch S, Schafmayer C, Valeria Maiorana M, Veneroni S, van Wezel T, Liu T, Westers H, Esteban-Jurado C, Ocaña T, Piqué JM, Andreu M, Jover R, Carracedo A, Xicola RM, Llor X, Castells A; EPICOLON Consortium, Dunlop M, Hofstra R, Lindblom A, Wijnen J, Peterlongo P, Hampe J, Ruiz-Ponte C, Castellví-Bel S.  The MLH1 c.1852_1853delinsGC (p.K618A) variant in colorectal cancer: genetic association study in 18,723 individuals.  PLoS One. 2014 Apr 17;9(4):e95022. (IF 3,2)
  21. Müller N, Schulte DM, Hillebrand S, Türk K, Hampe J, Schafmayer C, Brosch M,  von Schönfels W, Ahrens M, Zeuner R, Schröder JO, Blüher M, Gutschow C, Freitag-Wolf S, Stelmach-Mardas M, Saggau C, Schreiber S, Laudes M. B Lymphocyte Stimulator (BLyS) is expressed in human adipocytes in vivo and is related to obesity but not to insulin resistance. PLoS One. 2014 Apr 11;9(4):e94282 (IF 3,2)
  22. Næss S, Lie BA, Melum E, Olsson M, Hov JR, Croucher PJ, Hampe J, Thorsby E, Bergquist A, Traherne JA, Schrumpf E, Boberg KM, Schreiber S, Franke A, Karlsen TH. Refinement of the MHC risk map in a scandinavian primary sclerosing cholangitis population. PLoS One. 2014;9(12):e114486. (IF 3,2)

2013

  1. Jürgensen C, Brand J, Nothnagel M, Arlt A, Neser F, Habeck JO, Schreiber S, Stölzel U, Zeitz M, Hampe J. Prognostic relevance of gastric cancer staging by endoscopic ultrasound. Surgical Endoscopy 2012 2013 Apr;27(4):1124-9. (IF 3,2)
  2. Lascorz J, Bevier M, V Schönfels W, Kalthoff H, Aselmann H, Beckmann J, Egberts J, Buch S, Becker T, Schreiber S, Hampe J, Hemminki K, Schafmayer C, Försti A. Association study identifying polymorphisms in CD47 and other extracellular matrix pathway genes as putative prognostic markers for colorectal cancer. Int J Colorectal Dis 2013;28(2):173-81. (IF 2,4)
  3. Dunlop MG, Tenesa A, Farrington SM, Ballereau S, Brewster DH, Kossler T, Pharoah P, Schafmayer C, Hampe J, Völzke H, Chang-Claude J, Hoffmeister M, Brenner H, von Holst S, Picelli S, Lindblom A, Jenkins MA, Hopper JL, Casey G, Duggan D, Newcomb PA, Abulí A, Bessa X, Ruiz-Ponte C, Castellví-Bel S, Niittymäki I, Tuupanen S, Karhu A, Aaltonen L, Zanke B, Hudson T, Gallinger S, Barclay E, Martin L, Gorman M, Carvajal-Carmona L, Walther A, Kerr D, Lubbe S, Broderick P, Chandler I, Pittman A, Penegar S, Campbell H, Tomlinson I, Houlston RS. Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42 103 individuals. Gut 2013; 62(6):871-81 (IF 14,6)
  4. Siegert S, Hampe J, Schafmayer C, von Schönfels W, Egberts JH, Försti A, Chen B, Lascorz J, Hemminki K, Franke A, Nothnagel M, Nöthlings U, Krawczak M. Genome-wide investigation of gene-environment interactions in colorectal cancer. Hum Genet. 2013;132(2):219-31(IF 4,8)
  5. Noth R, Häsler R, Stüber E, Ellrichmann M, Schäfer H, Geismann C, Hampe J, Bewig B, Wedel T, Böttner M, Schreiber S, Rosenstiel P, Arlt A. Oral glutamine supplementation improves intestinal permeability dysfunction in a murine acute graft-vs.-host disease model. Am J Physiol Gastrointest Liver Physiol. 2013;304(7):G646-54. (IF 3,7)
  6. Schniewind B, Schafmayer C, Voehrs G, Egberts J, von Schoenfels W, Rose T, Kurdow R, Arlt A, Ellrichmann M, Jürgensen C, Schreiber S, Becker T, Hampe J. Endoscopic endoluminal vacuum therapy is superior to other regimens in managing anastomotic leakage after esophagectomy: a comparative retrospective study. Surg Endosc. 2013;27(10):3883-90 (IF 3,2)
  7. Gassling V, Hampe J, Açil Y, Braesen JH, Wiltfang J, Häsler R.Disease-associated miRNA-mRNA networks in oral lichen planus. PLoS One. 2013;8(5):e63015. (IF 3,2)
  8. Ahrens M, Ammerpohl O, von Schönfels W, … Röcken C, Siebert R, Schafmayer C, Hampe J. DNA methylation analysis in nonalcoholic Fatty liver disease suggests distinct disease-specific and remodeling signatures after bariatric surgery. Cell Metab 2013;18(2):296-302 (IF 17,5)
  9. Koch M, Jacobs G, Hampe J, Rosenstiel P, Krawczak M, Nöthlings U. Higher Fetuin-A Level Is Associated with Coexistence of Elevated Alanine Aminotransferase and the Metabolic Syndrome in the General Population. Metab Syndr Relat D 2013 Aug 24. (IF 1,9)
  10. Picelli S, Lorenzo Bermejo J, … Hampe J, Schafmayer C, Lindblom A. Meta-Analysis of Mismatch Repair Polymorphisms within the Cogent Consortium for Colorectal Cancer Susceptibility. PLoS One. 2013 Sep 6;8(9):e72091 (IF 3,2)
  11. Koch M, Jacobs G, Hampe J, Rosenstiel P, Krawczak M, Nöthlings U.Higher fetuin-A level is associated with coexistence of elevated alanine aminotransferase and the metabolic syndrome in the general population. Metab Syndr Relat D 2013;11(6):377-84 (IF 1,9)
  12. Picelli S, Lorenzo Bermejo J, Chang-Claude J, Hoffmeister M, Fernández-Rozadilla C, Carracedo A, Castells A, Castellví-Bel S; Members of EPICOLON Consortium-Gastrointestinal Oncology Group of the Spanish Gastroenterological Association, Naccarati A, Pardini B, Vodickova L, Müller H, Talseth-Palmer BA, Stibbard G, Peterlongo P, Nici C, Veneroni S, Li L, Casey G, Tenesa A, Farrington SM, Tomlinson I, Moreno V, van Wezel T, Wijnen J, Dunlop M, Radice P, Scott RJ, Vodicka P, Ruiz-Ponte C, Brenner H, Buch S, Völzke H, Hampe J, Schafmayer C, Lindblom A. Meta-analysis of mismatch repair polymorphisms within the cogent consortium for colorectal cancer susceptibility. PLoS One. 2013;8(9):e720 (IF 3,2)
  13. von Schönfels W, von Kampen O, Patsenker E, Stickel F, Schniewind B, Hinz S, Ahrens M, Balschun K, Egberts JH, Richter K, Landrock A, Sipos B, Will O, Huebbe P, Schreiber S, Nothnagel M, Röcken C, Rimbach G, Becker T, Hampe J, Schafmayer C. Metabolic signature of electrosurgical liver dissection. PLoS One. 2013;8:e72022 (IF 3,2)
  14. Klimosch SN, Försti A, Eckert J, Knezevic J, Bevier M, von Schönfels W, Heits N, Walter J, Hinz S, Lascorz J, Hampe J, Hartl D, Frick JS, Hemminki K, Schafmayer C, Weber AN. Functional TLR5 genetic variants affect human colorectal cancer survival. Cancer Res. 2013;73(24):7232-42 (IF 9,3)
  15. Siegert S, Yu Z, Wang-Sattler R, Illig T, Adamski J, Hampe J, Nikolaus S, Schreiber S, Krawczak M, Nothnagel M, Nöthlings U Diagnosing fatty liver disease: a comparative evaluation of metabolic markers, phenotypes, genotypes and established biomarkers. PLoS One. 2013;8(10):e76813 (IF 3,2)

2012

  1. Ammerpohl O, Pratschke J, Schafmayer C, Haake A, Faber W, von Kampen O, Brosch M, Sipos B, von Schönfels W, Balschun K, Röcken C, Arlt A, Schniewind B, Grauholm J, Kalthoff H, Neuhaus P, Stickel F, Schreiber S, Becker T, Siebert R, Hampe J. Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma. Int J Cancer. 2012; 130:1319-28. (IF 5,0)
  2. Helbig KL, Nothnagel M, Hampe J, Balschun T, Nikolaus S, Schreiber S, Franke A, Nothlings U. A case-only study of gene-environment interaction between genetic susceptibility variants in NOD2 and cigarette smoking in Crohn's disease aetiology. BMC Med Genet. 2012; 13:14, (IF 2,0)
  3. Brosch M, Ahrens M, Nothnagel M, Krawczak M, Laudes M, Sipos B, Becker T, Schreiber S, Röcken C, Schafmayer C, Hampe J. SFRS10-A Splicing Factor Gene Reduced in Human Obesity? Brosch M, von Schönfels W, Cell Metab 2012;15(3):265-6. (IF 17,5)
  4. Campa D, Sainz J, Pardini B, Vodickova L, Naccarati A, Rudolph A, Novotny J, Försti A, Buch S, von Schönfels W, Schafmayer C, Völzke H, Hoffmeister M, Frank B, Barale R, Hemminki K, Hampe J, Chang-Claude J, Brenner H, Vodicka P, Canzian F.  A Comprehensive Investigation on Common Polymorphisms in the MDR1/ABCB1 Transporter Gene and Susceptibility to Colorectal Cancer. PLoS One. 2012;7:e32784. (IF 3,2)
  5. Helbig KL, Nothnagel M, Hampe J, Balschun T, Nikolaus S, Schreiber S, Franke A, Nöthlings U. A case-only study of gene-environment interaction between genetic susceptibility variants in NOD2 and cigarette smoking in Crohn's disease aetiology. BMC Med Genet. 2012;13:14. (IF 2,0)
  6. Jürgensen C, Arlt A, Neser F, Fritscher-Ravens A, Stölzel U, Hampe J. Endoscopic ultrasound criteria to predict the need for intervention in pancreatic necrosis BMC Gastroenterology 2012, 12:48 (IF 2,3)
  7. Lascorz J, Bevier M, Schönfels WV, Kalthoff H, Aselmann H, Beckmann J, Egberts J, Buch S, Becker T, Schreiber S, Hampe J, Hemminki K, Försti A, Schafmayer C. Polymorphisms in the mitochondrial oxidative phosphorylation chain genes as prognostic markers for colorectal cancer. BMC Med Genet. 2012 Apr 30;13(1):31 (IF 2,0)
  8. Zeissig S, Murata K, Sweet L, Publicover J, Hu Z, Kaser A, Bosse E, Iqbal J, Hussain MM, Balschun K, Röcken C, Arlt A, Günther R, Hampe J, Schreiber S, Baron JL, Moody DB, Liang TJ, Blumberg RS. Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity. Nat Medicine. 2012; epub (IF 27,3)
  9. v. Schönfels W, Buch S, Wölk M, Aselmann H, Egberts JH, Schreiber S, Krawczak M, Becker T, Hampe J, Schafmayer C. Recurrence of gallstones after cholecystectomy is associated with ABCG5/8 genotype. J Gastroenterology 2012; in press (IF 4,5)
  10. von Kampen O, Buch S, Nothnagel M, …. Miquel JF, Schafmayer C, Hampe J. Genetic and functional identification of the likely causative variant for cholesterol gallstone disease at the ABCG5/8 lithogenic locus. Hepatology  2012; 57(6):2407-17 (IF 11,0)
  11. Fritsch C, Herrmann A, … Hampe J*, Brosch M. Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting. (*Correspondence & equal senior authorship) Genome Res 2012; 22(11):2208-18 (IF 14,6)

2011

  1. Stickel F, Buch S, Lau K, Meyer zu Schwabedissen H, Berg T, Ridinger M, Rietschel M, Schafmayer C, Braun F, Hinrichsen H, Günther R, Arlt A, Seeger M, Müller S, Seitz HK, Soyka M, Lerch MM, Lammert F, Sarrazin C, Kubitz R, Häussinger D, Hellerbrand C, Bröring D, Schreiber S, Spanagel R, Mann K, Datz C, Krawczak M, Wodarz N, Völzke H, Hampe J. Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in Caucasians. Hepatology 2011;53(1):86-95, (IF 11,0)
  2. Müller T, Buch S, Berg T, Hampe J, Stickel F. Distinct, alcohol-modulated effects of PNPLA3 genotype on progression of chronic hepatitis C. J Hepatol. 2011 55(3):732-3 (IF 11,3)
  3. Nothnagel M, Herrmann A, Wolf A, Schreiber S, Platzer M, Siebert R, Krawczak M, Hampe J. Technology-specific error signatures in the 1000 Genomes Project data. Hum Genet. 2011 130(4):505-16 (IF 4,8)
  4. Herrmann A, Haake A, Ammerpohl O, Martin-Guerrero I, Szafranski K, Stemshorn K, Nothnagel M, Kotsopoulos SK, RichterJ; Warner J, Olson J, Link DR, Schreiber S, Krawczak M, Platzer M, Nürnberg P, Siebert P, Hampe J. Pipeline for large-scale microdroplet bisulfite PCR-based sequencing allows the tracking of hepitype evolution in tumors. PLOS One 2011, 2011;6(7):e21332 (IF 3,2)
  5. Jacobs G, Hellmig S, Huse K, Titz A, Franke A, Kwiatkowski R, Ott S, Kosmahl M, Fischbach W, Lucius R, Klapper W, Fölsch UR, Hampe J, Schreiber S, Rosenstiel P. Polymorphisms in the 3'-untranslated region of the CDH1 gene are a risk factor for primary gastric diffuse large B-cell lymphoma. Haematologica. 2011;96(7):987-95 (IF 5,8)
  6. Association of genetic polymorphisms in ESR2, HSD17B1, ABCB1, and SHBG genes with colorectal cancer risk. Sainz J, Rudolph A, Hein R, Hoffmeister M, Buch S, von Schönfels W, Hampe J, Schafmayer C, Völzke H, Frank B, Brenner H, Försti A, Hemminki K, Chang-Claude Endocr-Relat Cancer. 2011 Mar 9;18(2):265-76. (IF 4,8)
  7. Comprehensive assessment of sequence variation within the copy number variable defensin cluster on 8p23 by target enriched in-depth 454 sequencing. Taudien S, Szafranski K, Felder M, Groth M, Huse K, Raffaelli F, Petzold A, Zhang X, Rosenstiel P, Hampe J, Schreiber S, Platzer M. BMC Genomics. 2011;12(1):243. (IF 3,9)
  8. Increased intestinal permeability and tight junction disruption by altered expression and localization of occludin in a murine graft versus host disease model. Noth R, Lange-Grumfeld J, Stüber E, Kruse ML, Ellrichmann M, Häsler R, Hampe J, Bewig B, Rosenstiel P, Schreiber S, Arlt A. BMC Gastroenterol. 2011;11:109. (IF 2,3)
  9. Stickel F, Trépo E, Moreno C, Hampe J. Reply to: "Modulation of the effect of PNPLA3 I148M mutation on steatosis and liver damage by alcohol intake in patients with chronic hepatitis C". J Hepatol. 2011;55(6):1471-2. (IF 11,3)
  10. Noth R, Stüber E, Häsler R, Nikolaus S, Kühbacher T, Hampe J, Bewig B, Schreiber S, Arlt A. Anti-TNF-α antibodies improve intestinal barrier function in Crohn's disease. J Crohns Colitis. 2011; 6(4):464-9 (IF 6,2)
  11. Kramer M, Huse K, Menzel U, Backhaus O, Rosenstiel P, Schreiber S, Hampe J, Platzer M.Constant splice-isoform ratios in human lymphoblastoid cells support the concept of a splico-stat. Genetics. 2011;187:761-70. (IF 5,9)

Publications until 2010

2010

  1. Tomlinson IP, Dunlop M, Campbell H, Zanke B, Gallinger S, Hudson T, Koessler T, Pharoah PD, Niittymäkix I, Tuupanenx S, Aaltonen LA, Hemminki K, Lindblom A, Försti A, Sieber O, Lipton L, van Wezel T, Morreau H, Wijnen JT, Devilee P, Matsuda K, Nakamura Y, Castellví-Bel S, Ruiz-Ponte C, Castells A, Carracedo A, Ho JW, Sham P, Hofstra RM, Vodicka P, Brenner H, Hampe J, Schafmayer C, Tepel J, Schreiber S, Völzke H, Lerch MM, Schmidt CA, Buch S, Moreno V, Villanueva CM, Peterlongo P, Radice P, Echeverry MM, Velez A, Carvajal-Carmona L, Scott R, Penegar S, Broderick P, Tenesa A, Houlston RS. COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer. Brit J Cancer. 2010;102:447-54, (IF 4.8)
  2. Karlsen TH, Franke A, Melum E, Kaser A, Hov JR, Balschun T, Lie BA, Bergquist A, Schramm C, Weismüller TJ, Gotthardt D, Rust C, Philipp EE, Fritz T, Henckaerts L, Weersma R, Stokkers P, Ponsioen CY, Wijmenga C, Sterneck M, Nothnagel M, Hampe J, Teufel A, Runz H, Rosenstiel P, Stiehl A, Vermeire S, Beuers U, Manns M, Schrumpf E, Boberg KM, Schreiber S. Genome-Wide Association Analysis in Primary Sclerosing Cholangitis. Gastroenterology. 2010;138(3):1102-11, (IF 16,7)
  3. Kramer M, Backhaus O, Rosenstiel P, Horn D, Klopocki E, Birkenmeier G, Schreiber S, Platzer M, Hampe J, Huse K. Analysis of relative gene dosage and expression differences of the paralogs RABL2A and RABL2B by Pyrosequencing. Gene. 2010;455(1-2):1-7, (IF 2,1)
  4. Muhle H, von Spiczak S, Gaus V, Kara S, Helbig I, Hampe J, Franke A, Weber Y, Lerche H, Kleefuss-Lie AA, Elger CE, Schreiber S, Stephani U, Sander T. Role of GRM4 in idiopathic generalized epilepsies analysed by genetic association and sequence analysis. Epilepsy Res. 2010;89(2-3):319-26, (IF 2,0)
  5. Hampe J, Schniewind B, Both M, Fritscher-Ravens A. Use of endoscopic NOTES closure device for full thickness suturing of a postoperative anastomotic esophageal leakage. Endoscopy 2010;42(7):595-8, (IF 5,0)
  6. Seeger M, Günther R, Hinrichsen H, Both M, Helwig U, Arlt A, Bräsen JH, Sipos B, Schafmayer C, Braun F, Bröring D, Schreiber S, Hampe J. Transcapsular hepatic collaterals and communicating ectopic varices in chronic portal vein thrombosis. Radiology 2010; 257(2):568-78, (IF 6,8)
  7. Ahrens M; Schulte T, Egberts JH, Schafmayer C, Hampe J, Fritscher-Ravens A, Broering DC, Schniewind B. Drainage of esophageal leakage using endoscopic vacuum therapy: a prospective pilot study. Endoscopy 2010; 42(9):693-698, (IF 5,0)
  8. Fritscher-Ravens A, Hampe J, Milla P, Grange P, Schiffmann S, von Herbay A, Eisenberger E, Ghanbari A, Nilges A, Ghadimi MP, Koehler P, Knoefel WT. Clip closure vs endoscopic suturing vs thorascoscopic repair of an iatrogenic esophageal perforation: A randomized comparative long term survival study in a porcine model. Gastrointest Endosc 2010; 72(5):1020-6, (IF 5,3)
  9. Lascorz J, Försti A, Chen B, Buch S, Steinke V, Rahner N, Holinski-Feder E, Morak M, Schackert HK, Görgens H, Schulmann K, Goecke T, Kloor M, Engel C, Büttner R, Kunkel N, Weires M, Hoffmeister M, Pardini B, Naccarati A, Vodickova L, Novotny J, Schreiber S, Krawczak M, Bröring CD, Völzke H, Schafmayer C, Vodicka P, Chang-Claude J, Brenner H, Burwinkel B, Propping P, Hampe J, Hemminki K. Genome-wide association study for colorectal cancer identifies risk polymorphisms in German familial cases and implicates MAPK signalling pathways in disease susceptibility. Carcinogenesis 2010; 31(9):1612-9, (IF 5,3)
  10. von Spiczak S, Muhle H, Helbig I, de Kovel CG, Hampe J, Gaus V, Koeleman BP, Lindhout D, Schreiber S, Sander T, Stephani U.Association Study of TRPC4 as a Candidate Gene for Generalized Epilepsy with Photosensitivity. Neuromol Med 2010;12(3):292-9, (IF 3,6)
  11. Sinha R, Lenser T, Jahn N, Gausmann U, Friedel S, Szafranski K, Huse K, Rosenstiel P, Hampe J, Schuster S, Hiller M, Backofen R, Platzer M. TassDB2 - A comprehensive database of subtle alternative splicing events. BMC Bioinformatics 2010;11: 216, (IF 2,5)
  12. Taudien S, Groth M, Huse K, Petzold A, Szafranski K, Hampe J, Rosenstiel P, Schreiber S, Platzer M. Haplotyping and copy number estimation of the highly polymorphic human beta-defensin locus on 8p23 by 454 amplicon sequencing. BMC Genomics. 2010;11: 252, (IF 3,9)
  13. Schniewind B, Schafmayer C, Both M, Arlt A, Fritscher-Ravens A, Hampe J. Ingrowth and device disintegration in an intralobar abscess cavity during endosponge therapy for esophageal anastomotic leakage. Endoscopy 2010; epub, (IF 5,0)
  14. Buch S, Schafmayer C, Völzke H, Seeger M, Miquel JF, Sookoian S, Egberts JH, Arlt A, Pirola CJ, Lerch MM, John U, Franke A, von Kampen O, Brosch M, Nothnagel M, Kratzer W, Boehm BO, Bröring CD, Schreiber S, Krawczak M, Hampe J. Evaluation of genome-wide loci of serum bilirubin levels as predictors of gallstone composition and gallstone risk. Gastroenterology2010; 138(3):1102-11, (IF 16,7)
  15. Nothnagel M, Wolf A, Herrmann A, Szafranski K, Vater I, Brosch M, Huse K, Siebert R, Platzer M, Hampe J, Krawczak M. Statistical inference of allelic imbalance from transcriptome data. Hum Mutat 2010, 32(1):98-106, (IF 6,9)

2009

  1. Schafmayer C, Buch S, Völzke H, von Schönfels W, Egberts JH, Schniewind B, Brosch M, Ruether A, Franke A, Mathiak M, Sipos B, Henopp T, Catalcali J, Hellmig S, Elsharawy A, Katalinic A, Lerch MM, John U, Fölsch UR, Fändrich F, Kalthoff H, Schreiber S, Krawczak M, Tepel J, Hampe J. Investigation of the colorectal cancer susceptibility region on chromosome 8q24.21 in a large German case-control sample. Int J Cancer. 2009;124(1):75-80, (IF 5,0)
  2. Elsharawy A, Hundrieser B, Brosch M, Wittig M, Huse K, Platzer M, Becker A, Simon M, Rosenstiel P, Schreiber S, Krawczak M, Hampe J. Systematic evaluation of the effect of common SNPs on pre-mRNA splicing. Hum Mutat. 2009;30(4):625-32, (IF 5,1)
  3. Friedrich N, Völzke H, Hampe J, Lerch MM, Jørgensen T. Known risk factors do not explain disparities in gallstone prevalence between Denmark and northeast Germany. Am J Gastroenterology 2009;104:89-95, (IF 10,7)
  4. Seeger M, Bewig B, Günther R, Schafmayer C, Vollnberg B, Rubin D, Hoell C, Schreiber S, Fölsch UR, Hampe J. Terminal Part of Thoracic Duct: High-Resolution US Imaging. Radiology 2009; 52(3):897-904, (IF 6,8)
  5. Arlt A, Bauer I, Schafmayer C, Tepel J, Sebens-Müerköster S, Brosch M, Röder C, Kalthoff H, Hampe J, Moyer MP, Fölsch UR, Schäfer H. Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of Nuclear factor E2-related factor 2 (Nrf2). Oncogene 2009; 28(45):3983-96, (IF 8,4)
  6. Möckelmann N, von Schönfels W, Buch S, von Kampen O, Sipos B, Egberts JH, Rosenstiel P, Franke A, Brosch M, Hinz S, Röder C, Kalthoff H, Fölsch UR, Krawczak M, Schreiber S, Bröring CD, Tepel J, Schafmayer C, Hampe J. Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal BMC Cancer 2009 20;9:79, (IF 3,3)

2008

  1. Schafmayer C, Freitag-Wolf S, Wolken H, Wittig M, Timm B, von Eberstein H, Vogel I, Dittrich H, Belz J, Quäschling R, Shekarriz H, Mendel V, Neugebauer W, Kallinowski F, Schafmayer A, Klima J, Völzke H, Fölsch UR, Fändrich F, Krawczak M, Schreiber S, Tepel J, Hampe J. Increased heritability of gallstone disease in early onset cases. Liver Int 2008;28(6):895-7, (IF 4,8)
  2. Melum E, Buch S, Schafmayer C, Kalthoff H, Tepel J, Schreiber S, Karlsen TH, Hampe J. Investigation of cholangiocarcinoma associated NKG2D polymorphisms in colorectal carcinoma. Int J. Cancer 2008, 123(1):241-2, (IF 5,0)
  3. Schürmann M, Kwiatkowski R, Albrecht M, Fischer A, Hampe J, Müller-Quernheim J, Schwinger E, Schreiber S. Study of Toll-Like Receptor Gene Loci in Sarcoidosis. Clin Exp Immunol 2008, 152(3):423-31, (IF 3,0)
  4. Tenesa A, Farrington SM, … Schafmayer C, Tepel J, Schreiber S, Völzke H, Schmidt CO, Hampe J, … Campbell H, Dunlop MG. Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet 2008, 40(5):631-7, (IF 29,3)
  5. Huse K, Taudien S, Groth M, Rosenstiel P, Szafranski K, Hiller M, Hampe J, Junker K, Schubert J, Schreiber S, Birkenmeier G, Krawczak M, Platzer M. Genetic Variants of the Copy Number Polymorphic ß-Defensin Locus are Associated with Sporadic Prostate Cancer. Tumor Biol 2008;29(2):83-92, (IF 3,6)
  6. Houlston RS, Webb E, ... Hampe J, Buch S, Schafmayer C, … Dunlop MG. Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat Genet. 2008 Dec;40(12):1426-35, (IF 29,3)
  7. Franke A, Fischer A, Nothnagel M, Becker C, Grabe N, Till A, Lu T, Müller-Quernheim J, Wittig M, Hermann A, Balschun T, Hofmann S, Niemiec R, Schulz S, Hampe J, Nikolaus S, Nürnberg P, Krawczak M, Schürmann M, Rosenstiel P, Nebel A, Schreiber S. Genome-wide association analysis in sarcoidosis and Crohn's disease unravels a common susceptibility locus on 10p12.2. Gastroenterology. 2008 Oct;135(4):1207-15, (IF 16,7)

2007

  1. Hampe J, Franke F, Rosenstiel P, Till A, Teuber M, Huse K, Albrecht M, Häsler R, Sipos B, Mayr G, De La Vega FM, Briggs J, Günther S, Prescott NJ, Onnie CM, Fölsch UR, Lengauer T, Platzer M, Mathew CG, Krawczak M, Schreiber S. A genome-wide association scan of non-synonymous SNPs identifies a susceptibility variant for Crohn disease in the autophagy-related 16-like (ATG16L1) gene. Nat. Genet. 2007 Feb;39(2):207-211, (IF 29,3)
  2. Karlsen TH, Boberg KM, Vatn M, Bergquist A, Hampe J, Schrumpf E, Thorsby E, Schreiber S, Lie BA. Different HLA class II associations in ulcerative colitis patients with and without primary sclerosing cholangitis. Genes Immun 2007 Apr;8(3):275-8, (IF 2,9)
  3. Fisher E, Nitz I, Lindner I, Rubin D, Boeing H, Mohlig M, Hampe J, Schreiber S, Schrezenmeir J, Doring F. Candidate gene association study of type 2 diabetes in a nested case-control study of the EPIC-Potsdam cohort - Role of fat assimilation. Mol Nutr Food Res. 2007 Feb;51(2):185-91, (IF 4,6)
  4. Schafmayer C, Buch S, Egberts J, Franke A, Brosch M, El Sharawy A, Katalinic A, Kremer B, Fölsch UR, Krawczak M, Fändrich F, Schreiber S, Tepel J, Hampe J. Genetic Investigation of DNA-Repair Pathway Genes PMS2, MLH1, MSH2, MSH6, MUTYH, OGG1 and MTH1 in Sporadic Colon Cancer. Int J Cancer 2007;121(3):555-8, (IF 5,0)
  5. Franke A, Rosenstiel P, Karlsen TH, Balschun T, von Kampen O, Sina C, Hampe J, Solberg C, Vatn MH, for the IBSEN study group, Schreiber S. No association between the TUCAN (CARD8) Cys10Stop mutation and inflammatory bowel disease (IBD) in a large retrospective German and a clinically well-characterized Norwegian sample. Gastroenterology 2007, May;132(5):2080-1, (IF 16,7)
  6. Prescott NJ, Fisher SA, Franke A, Hampe J, Onnie C, Todhunter C, Soars D, Bagnall R, Mirza MM, Sanderson J, Forbes A, Mansfield J, Lewis CM, Schreiber S, Mathew CG. A non-synonymous SNP in ATG16L1 is a risk factor for ileal Crohn’s disease and is independent of CARD15 and IBD5. Gastroenterology 2007; May;132(5):1665-71, (IF 16,7)
  7. Buch S, Schafmayer C, Völzke H, Becker C, Franke A, von Eller-Eberstein H, Kluck C, Bäßmann I, Brosch M, Lammert F, Miquel JF, Nervi F, Wittig M, Rosskopf D, Timm B, Höll C, Seeger M, ElSharawy A, Fändrich F, Fölsch UR, Krawczak M, Schreiber S, Nürnberg P, Tepel J, Hampe J. A genome-wide association scan identifies the hepatic cholesterol transporter ABCG5/ABCG8 as a susceptibility factor for human gallstone disease. Nat Genet 2007 Aug;39(8):995-9, (IF 29,3)
  8. Wollstein A, Herrmann A, Wittig M, Nothnagel M, Franke A, Nurnberg P, Schreiber S, Krawczak M, Hampe J. Efficacy assessment of SNP sets for genome-wide disease association studies. Nucleic Acids Res. 2007;35(17):e113, (IF 9,1)
  9. Schafmayer C, Volzke H, Buch S, Egberts J, Spille A, von Eberstein H, Franke A, Seeger M, Hinz S, Elsharawy A, Rosskopf D, Brosch M, Krawczak M, Foelsch UR, Schafmayer A, Lammert F, Schreiber S, Faendrich F, Hampe J, Tepel J. Investigation of the Lith6 candidate genes APOBEC1 and PPARG in human gallstone disease. Liver Int. 2007 Sep;27(7):910-9, (IF 4,8)
  10. Franke A, Hampe J, Rosenstiel P, Becker C, Wagner F, Hasler R, Little RD, Huse K, Ruether A, Balschun T, Wittig M, Elsharawy A, Mayr G, Albrecht M, Prescott NJ, Onnie CM, Fournier H, Keith T, Radelof U, Platzer M, Mathew CG, Stoll M, Krawczak M, Nurnberg P, Schreiber S.Systematic association mapping identifies NELL1 as a novel IBD disease gene. PLoS ONE. 2007 Aug 8;2(1):e691, (IF 3,2)
  11. Brenmoehl J, Herfarth H, Gluck T, Audebert F, Barlage S, Schmitz G, Froehlich D, Schreiber S, Hampe J, Scholmerich J, Holler E, Rogler G. Genetic variants in the NOD2/CARD15 gene are associated with early mortality in sepsis patients. Intens Care Med. 2007 Sep;33(9):1541-8, (IF 7,2)
  12. Schwarz S, Volzke H, Baumeister SE, Hampe J, Doren M. Menopausal hormone therapy and gallbladder disease: the Study of Health in Pomerania (SHIP). Clin Endocrinol. 2007 Jul;67(1):51-9, (IF 3,4)
  13. Rosenstiel P, Huse K, Franke A, Hampe J, Reichwald K, Platzer C, Roberts R, Mathew C, Platzer M, Schreiber S. Functional characterization of two novel 5' untranslated exons reveals a complex regulation of NOD2 protein expression. BMC Genomics, 2007;8:472, (IF 3,9)
  14. Tomlinson IP, Webb E, …. Schafmayer C, Buch S, Völzke H, Hampe J, … Dunlop MG, Houlston RS. A genome-wide association study identifies novel colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet 2007 Aug;39(8):995-9, (IF 29,3)

2006

  1. Zheng W, Rosenstiel P, Huse K, Sina C, Valentonyte R, Mah N, Zeitlmann L, Grosse J, Costello CM, Onnie C, Mathew C, Platzer M, Schreiber S, Hampe J. Evaluation of AGR2 and AGR3 as candidate genes for inflammatory bowel disease. Genes Immun 2006; 7(1):11-8, (IF 2,9)
  2. Hiller M, Huse K, Szafranski K, Jahn N, Hampe J, Schreiber S, Backofen R, Platzer M. SNPs in NAGNAG acceptors are highly predictive for variations of alternative splicing. Am J Hum Genet; 2006 Feb;78(2):291-302, (IF 10,9)
  3. Becker T, Valentonyte R, Croucher PJP, Strauch K, Schreiber S, Hampe J, Knapp M. Identification of probable genotyping errors by consideration of haplotypes. Eur J Hum Genet; 2006;14(4):450-8, (IF 4,3)
  4. Ott SJ, El Mokhtari NE, Musfeldt M, Hellmig S, Freitag S, Rehman A, Kühbacher T, Namsolleck P, Blaut M, Hampe J, Sahly H, Reinecke A, Haake N, Günther R, Krüger D, Lins M, Herrmann G, Fölsch UR, Simon R, Schreiber S. Detection of Diverse Bacterial Signatures in Atherosclerotic Lesions of Patients with Coronary Heart Disease Circulation, 2006;113(7):929-37, (IF 14,4)
  5. JenischS, Hampe J, Elder JT, Nair R, Stuart P, Voorhees JJ, Schreiber S, Kabelitz D, Christophers E, Weichenthal M. CARD15 mutations in patients with plaque-type psoriasis and psoriatic arthritis: lack of association. Arch Dermatol Res 2006 Mar;297(9):409-11, (IF 1,9)
  6. Rosenstiel P, Huse K, Till A, Hampe J, Hellmig S, Sina C, Billmann S, von Kampen O, Waetzig GH, Platzer M, Seegert D, Schreiber S. A short isoform of NOD2/CARD15 (NOD2-S) is an endogenous inhibitor of NOD2/RIP2-induced signalling pathways. PNAS 2006;103(9):3280-5, (IF 9,6)
  7. Franke A, Wollstein A, Teuber M, Wittig M, Lu T, Hoffmann K, Nürnberg P, Krawczak M, Schreiber S, Hampe J. GENOMIZER - An Integrated Analysis System for Genome-Wide Association Data. Hum Mutat 2006, 27(6):583-8, (IF 5,1)
  8. Fisher SA, Hampe J, Onnie CM, Daly MJ, Curley C, Purcell S, Sanderson S, Mansfield J, Annese V, Forbes A, Lewis CM, Schreiber S, Rioux JD, Mathew CG Direct or indirect association in a complex disease: the role of SLC22A4 and SLC22A5 functional variants in Crohn disease. Hum Mutat 2006, 27(8):778-85, (IF 5,1)
  9. Medici V, Mascheretti S, Croucher PJ, Stoll M, Hampe J, Grebe J, Sturniolo GC, Solberg C, Jahnsen J, Moum B, Schreiber S, Vatn MH. Extreme heterogeneity in CARD15 and DLG5 Crohn disease-associated polymorphisms between German and Norwegian populations. Eur J Hum Genet. 2006 Apr;14(4):459-468, (IF 4,3)
  10. Lindner I, Rubin D, Helwig U, Nitz I, Hampe J, Schreiber S, Schrezenmeir J, Doring F. The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population. Mol Nutr Food Res. 2006;50(3):270-4, (IF 4,6)
  11. Hellmig S, Ott S, Rosenstiel P, Robert Folsch U, Hampe J, Schreiber S. Genetic variants in matrix metalloproteinase genes are associated with development of gastric ulcer in H. Pylori infection. Am J Gastroenterol. 2006 Jan;101(1):29-35, (IF 10,7)
  12. Flachsbart F, Croucher PJ, Nikolaus S, Hampe J, Cordes C, Schreiber S, Nebel A. Sirtuin 1 (SIRT1) sequence variation is not associated with exceptional human longevity. Exp Gerontol. 2006 Jan;41(1):98-102, (IF 3,4)
  13. Groth M, Huse K, Reichwald K, Taudien S, Hampe J, Rosenstiel P, Birkenmeier P, Schreiber S, Platzer M. Method for preparing single-stranded DNA templates for Pyrosequencing™ using vector ligation and universal biotinylated primers. Anal Biochem 2006 356(2):194-201, (IF 2,2)
  14. ElSharawy A, Manaster C, Teuber M, Rosenstiel P, Kwiatkowski R, Huse K, Platzer M, Becker A, Nürnberg P, Schreiber S, Hampe J. SNPSplicer – Systematic analysis of SNP-dependent splicing in genotyped cDNAs. Hum Mutat 2006 27(11):1129-34, (IF 5,1)
  15. Platzer M, Hiller M, Szafranskzy K, Jahn N, Hampe J, Schreiber S, Backofen R, Huse K. Splice acceptor SNPs - no hypervariability but sequencing errors. Nat Biotechnol 2006 24(9):1068-70, (IF 41,5)
  16. Schafmayer C, Tepel J, Franke A, Buch S, Lieb S, Seeger M, Lammert F, Kremer B, Fölsch UR, Fändrich F, Schreiber S, Hampe J. Investigation of the Lith candidate genes ABCB11 and LXRA in human gall stone disease. Hepatology 2006 44(3):650-7, (IF 11,0)
  17. Rosenstiel, P., Hellmig, S., Hampe, J., Ott, S., Till, A., Fischbach, W., Sahly, H., Lucius, R., Folsch, U. R., Philpott, D., Schreiber, S. Influence of polymorphisms in the NOD1/CARD4 and NOD2/CARD15 genes on the clinical outcome of Helicobacter pylori infection. Cell Microbiol 8, 1188-1198 (2006), (IF 5,9)
  18. Krawczak M, Thomas NST, Hundrieser B, Mort M, Wittig M, Hampe J, Cooper DN. Single Base-Pair Substitutions in Exon–Intron Junctions of Human Genes: Nature, Distribution, and Consequences for mRNA Splicing. Hum Mutat 2006 epub, (IF 5,1)
  19. Steffens M, Lamin C, Illig T, Bettecken T, Vogler R, Entz P, Suk EY, Toliat MR, Klopp N, Caliebe A, König IR, Köhler K, Lüdemann J, Lacava AD, Fimmers R, Ziegler A, Wolf A, Krawczak M, Nürnberg P, Hampe J, Schreiber S, Meitinger T, Wichmann HE, Roeder K, Wienker TF, Baur MP. SNP-based analysis of genetic substructure in the German population. Hum Hered 2006; 62(1):20-29, (IF 1,4)
  20. Karlsen TH, Hampe J, Wiencke K, Schrumpf E, Thorsby E, Lie BA, Broomé U, Schreiber S, Boberg KM. Genetic polymorphisms associated with inflammatory bowel disease do not confer risk for primary sclerosing cholangitis. Am J. Gastroenterol 2006; Nov 22;6:36, (IF 10,7)
  21. Schafmayer C, Hartleb J, Tepel J, Albers S, Freitag S, Völzke H, Timm B, Buch S, Seeger M, Kremer B, Fölsch UR, Fändrich F, Krawczak M, Schreiber S, Hampe J. Predictors of gallstone composition in 1025 symptomatic gallstones from Northern Germany. BMC Gastroenterology 2006; 6: 36, (IF 2,3)
  22. Louis EJ, Watier HE, Schreiber S, Hampe J, Taillard F, Olson A, Thorne N, Zhang H, Colombel JF. Polymorphism in IgG Fc receptor gene FCGR3A and response to infliximab in Crohn's disease: a subanalysis of the ACCENT I study. Pharmacogenomics 2006;16:911-914, (IF 3,2)

2005

  1. Valentonyte R*, Hampe J*, Huse K, Rosenstiel P, Albrecht M, Stenzel M, Nagy M, Gaede KI, Jenisch S, Platzer M, Koch A, Lengauer T, Seegert D, Schwinger S, Krawczak M, Müller-Quernheim J, Schürmann M, Schreiber S. Sarcoidosis is associated with a truncating splice site mutation in the BTNL2 gene. Nat Genet 2005. 37(4):357-64. (*equal contribution and correspondence by JH), (IF 29,3)
  2. Entz P, Toliat MR, Hampe J, Valentonyte R, Jenisch S, Nurnberg P, Nagy M. New strategies for efficient typing of HLA class-II loci DQB1 and DRB1 by using Pyrosequencing. Tissue Antigens 2005;65(1):67-80, (IF 2,1)
  3. Hellmig S, Mascheretti S, Renz J, Frenzel H, Jelschen F, Rehbein JK, Folsch U, Hampe J, Schreiber S. Haplotype analysis of the CD11 gene cluster in patients with chronic Helicobacter pylori infection and gastric ulcer disease. Tissue Antigens. 2005 Mar;65(3):271-4, (IF 2,1)
  4. Hellmig S, Hampe J, Fölsch UR, Schreiber S. Role of IL-10 promotor haplotypes in Helicobacter pylori associated gastric inflammation. Gut 2005; 54(6):888, (IF 14,6)
  5. Manaster C, Valentonyte R, Teuber M, Zheng W, Schreiber S, Hampe J. SGCaller - Automated assistance for genotypes measured by sequencing. Biotechniques 2005; 38(4):544 – 546, (IF 2,9)
  6. Valentonyte R, Hampe J, Croucher PJP, Müller-Quernheim J, Schwinger E, Schreiber S, Schürmann M. Study of C-C Chemokine receptor 2 alleles in sarcoidosis with emphasis on family based analysis. Am J  Resp Crit Care Medicine 2005; 171(10):1136-41, (IF 12,9)
  7. Manaster C, Zheng W, Teuber M, Wächter S, Döring F, Schreiber S, Hampe J. InSNP – a tool for automated detection and visualization of SNPs and InDels. Human Mutat, 2005; 26:1-9, (IF 5,1)
  8. Hillmer AM, Hanneken S, Ritzmann S, Becker T, Freudenberg J, Brockschmidt FF, Flaquer A, Freudenberg-Hua Y, Jamra RA, Metzen C, Heyn U, Schweiger N, Betz RC, Hampe J, Schreiber S, Schulze TG, Hennies HC, Schumacher J, Propping P, Ruzicka T, Cichon S, Wienker TF, Kruse R, Nöthen MM. Genetic Variation in the Human Androgen Receptor Gene is the Major Determinant of Common Early Onset Androgenetic Alopecia. Am J Hum Genet 2005, 77(1):140-8, (IF 10,9)
  9. Folster-Holst R, Stoll M, Koch WA, Hampe J, Christophers E, Schreiber S. Lack of association of SPINK5 polymorphisms with nonsyndromic atopic dermatitis in the population of Northern Germany. Brit J Dermatol. 2005 Jun;152(6):1365-7, (IF 4,2)
  10. Hellmig S, Ott S, Musfeldt M, Kosmahl M, Rosenstiel P, Stüber E, Hampe J, Fölsch UR, Schreiber S. Life-Threatening Chronic Enteritis Due to Colonization of the Small Bowel with Stenotrophomonas maltophilia. Gastroenterology 2005;129(2):706-12, (IF 16,7)
  11. Costello CM, Mah N, Hasler R, Rosenstiel P, Waetzig GH, Hahn A, Lu T, Gurbuz Y, Nikolaus S, Albrecht M, Hampe J, Lucius R, Kloppel G, Eickhoff H, Lehrach H, Lengauer T, Schreiber S. Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays. PLoS Med. 2005 Aug;2(8):e199, (IF 14,4)
  12. de Vrese M, Winkler P, Rautenberg P, Harder T, Noah C, Laue C, Ott S, Hampe J, Schreiber S, Heller K, Schrezenmeir J. Effect of Lactobacillus gasseri PA 16/8, Bifidobacterium longum SP 07/3, B. bifidum MF 20/5 on common cold episodes: A double blind, randomized, controlled trial. Clin Nutr. 2005 Aug;24(4):481-491, (IF 4,4)
  13. Hellmig S, Fischbach W, Goebeler-Kolve ME, Folsch UR, Hampe J, Schreiber S. Association study of a functional Toll-like receptor 4 polymorphism with susceptibility to gastric mucosa-associated lymphoid tissue lymphoma. Leukemia Lymphoma. 2005 Jun;46(6):869-72, (IF 2,8)
  14. Hellmig S, Fischbach W, Goebeler-Kolve ME, Folsch UR, Hampe J, Schreiber S. A functional promotor polymorphism of TNF-alpha is associated with primary gastric B-Cell lymphoma. Am J Gastroenterol. 2005;100(12):2644-9, (IF 10,7)
  15. Hellmig S, Titz A, Steinel S, Ott S, Folsch UR, Hampe J, Schreiber S. Influence of IL-1 gene cluster polymorphisms on the development of H. pylori associated gastric ulcer. Immunol Lett. 2005;100(2):107-12, (IF 2,5)
  16. Lindner I, Helwig U, Rubin D, Li Y, Fisher E, Boeing H, Mohlig M, Spranger J, Pfeiffer A, Hampe J, Schreiber S, Doring F, Schrezenmeir J. Putative association between a new polymorphism in exon 3 (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes mellitus in two independent Caucasian study populations. Mol Nutr Food Res. 2005 Oct;49(10):972-6, (IF 4,6)

2004

  1. Hampe J, Valentonyte R, Manaster C, Teuber M, Jenisch S, Entz P, Nagy M, Schreiber S. A non-electrophoretic method for high-throughput HLA-DRB1 group genotyping. Biotechniques 2004; 36(1):148-51, (IF 2,9)
  2. Stenzel A, Lu T, Koch WA, Hampe J, Guenther SM, De La Vega FM, Krawczak M, Schreiber S. Patterns of linkage disequilibrium in the MHC region on human chromosome 6p. Hum Genet. 2004 Mar;114(4):377-85, (IF 4,8)
  3. Ott SJ, Musfeldt M, Wenderoth DF, Hampe J, Brant O, Fölsch UR, Timmis KN, Schreiber S. Reduction in diversity of the colonic mucosa-associated bacterial microflora in patients with active inflammatory bowel disease. Gut 2004; 53(5): 685-93, (IF 14,6)
  4. Mascheretti S, Hinrichsen H, Ross S, Buggisch P, Hampe J, Foelsch UR, Schreiber S. Genetic variants in the CCR gene cluster and spontaneous viral elimination in Hepatitis C infected patients. Clin Exp Immunol 2004; 136(2):328-33, (IF 3,0)
  5. Stoll M, Corneliussen M, Costello CM, Waetzig GH, Mellgard B, Rosenstiel P, Albrecht M, Croucher PJP, Seegert D, Nikolaus S, Hampe J, Lengauer T, Pierrou S, Foelsch UR, Mathew CG, Lagerstrom-Fermer M, Schreiber S. Genetic variation in DLG5 confers susceptibility to inflammatory bowel disease. Nat Genet. 2004; 36(5):476-80, (IF 29,3)
  6. Utting M, Hampe J, Platzer M, Huse K. Locking of 3' ends of single-stranded DNA templates for improved Pyrosequencing performance. Biotechniques 2004; 37(1): 66-7, 70-3, (IF 2,9)
  7. Ott SJ, Musfeldt M, Ullmann U, Hampe J, Schreiber S. Quantification of intestinal bacterial populations by real-time PCR with a universal primer set and minor groove binder probes: a global approach to the enteric flora. J Clin Microbiol. 2004;42(6):2566-72, (IF 3,9)
  8. Hiller M, Huse K, Szafranski K, Jahn N, Hampe J, Schreiber S, Backofen R, Platzer M. Widespread occurrence of alternative splicing at NAGNAG acceptors contributes to proteome plasticity. Nat Genet. 2004; 36(12):1255-7, (IF 29,3)
  9. Hellmig S, Vollenberg S, Goebeler-Kolve ME, Fischbach W, Hampe J, Fölsch UR, Schreiber S. IL-1 gene cluster polymorphisms and development of primary gastric B-cell lymphoma in H. pylori infection. Blood 2004; 104: 2994-5, (IF 10,4)
  10. Zwiers A, Seegers D, Heijmans R, Koch A, Hampe J, Nikolaus S, Pena AS, Schreiber S, Bouma G. Definition of polymorphisms and haplotypes in the interleukin-12B gene: association with IL-12 production but not with Crohn's disease. Genes Immun. 2004; 5(8):675-7, (IF 2,9)
  11. Ott SJ, Musfeldt M, Timmis KN, Hampe J, Wenderoth DF, Schreiber S. In vitro alterations of intestinal bacterial microbiota in fecal samples during storage. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE 2004; 50(4):237-45, (IF 2,4)

2003

  1. Croucher PJP, Mascheretti S, Hampe J, Huse K, Frenzel H, Stoll M, Lu T, Nikolaus S, Yang SK, Krawczak M, Kim WH, Schreiber S. Haplotype structure and association to Crohn’s disease of CARD15 mutations in two ethnically divergent populations. Eur J Hum Genet 2003; 11: 6-16, (IF 4,3)
  2. Mirza MM, Fisher SA, King K, Cuthbert AP, Hampe J, Sanderson J, Mansfield J, Donaldson P, Macpherson A, Forbes A, Schreiber S, Lewis CM, Mathew CG. Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease. Am J Hum Genet 2003; 72: 1018-1022, (IF 4,3)
  3. Hampe J, Heymann K, Krawczak M, Schreiber S. Association of inflammatory bowel disease with indicators for childhood antigen and infection exposure. Intl J Colorectal Dis 2003; 18:413-417, (IF 2,3)
  4. King K, Moody A, Fisher SA, Mirza MM, Cuthbert AP, Hampe J, Sutherland-Craggs A, Sanderson J, MacPherson AJ, Forbes A, Mansfield J, Schreiber S, Lewis CM, Mathew CG. Genetic variation in the IGSF6 gene and lack of association with inflammatory bowel disease. Eur J Immunogenetics 2003; 30(3): 187-90, (IF 1,9)
  5. Herbon N, Werner M, Braig C, Gohlke H, Dütsch G, Illig T, Altmüller J, Hampe J, Lantermann A, Schreiber S, Bonifacio E, Ziegler A, Schwab S, Wildenauer D, van den Boom D, Braun A, Knapp M, Reitmeir P, Wjst M. High-resolution SNP scan of chromosome 6p21 in pooled samples from patients with complex diseases Genomics 2003; 81: 510–518, (IF 2,2)
  6. Croucher PJP, Mascheretti S, Mathew CG, Foelsch UR, Hampe J, Schreiber S. Lack of Association Between the C3435T MDR1 Gene Polymorphism and Inflammatory Bowel Disease in Two Independent Northern European Populations. Gastroenterology 2003; 125(6):1919-20, (IF 16,7)
  7. Giallourakis, C, Stoll M, Miller K, Hampe J, Daly MJ, Lander ES, Schreiber S, Rioux JD. IBD5 is a General Risk Factor for Inflammatory Bowel Disease: Replication of Association with Crohn Disease and Identification of a Novel Association with Ulcerative Colitis. Am. J. Hum. Genet. 2003; 73(1): 205-11, (IF 10,9)
  8. King K, Moody A, Fisher SA, Mirza MM, Cuthbert AP, Hampe J, Sutherland-Craggs A, Sanderson J, MacPherson AJ, Forbes A, Mansfield J, Schreiber S, Lewis CM, Mathew CG. Genetic variation in the IGSF6 gene and lack of association with inflammatory bowel disease. Eur J Immunogenet. 2003; 30(3):187-90, (IF 1,9)
  9. Hellmig S, Hampe J, Schreiber S. Helicobacter pylori infection in Africa and Europe –enigma of host genetics. Gut 2003; 52(12):1799, (IF 14,6)
  10. Hampe J, Schreiber S, Krawczak M. Entropy-based SNP selection for genetic association studies. Hum Genet 2003, 114(1):36-43, (IF 4,8)
  11. Shaw SS, Hampe J, White R, Mathew CG, Curran ME, Schreiber S. Stratification by CARD15 variant genotype in a genome-wide search for inflammatory bowel disease susceptibility loci. Hum Genet 2003; 113(6):514-21, (IF 4,8)
  12. Schürmann M , Valentonyte R, Hampe J, Müller-Quernheim J, Schwinger E, Schreiber S. CARD15 gene mutations in sarcoidosis. Eur Respir J 2003; 22(5):748-54, (IF 7,6)

2002

  1. Hampe J, Frenzel H, Mirza MM, Croucher PJP, Cuthbert A, Mascheretti S, Huse K, Platzer M, Bridger S, Meyer B, Nürnberg P, Stokkers P, Krawczak M, Mathew CG, Curran M, Schreiber S. Evidence for an NOD2 independent susceptibility locus for Inflammatory Bowel Disease on Chromosome 16p. PNAS 2002; 99(1):321-6, (IF 9,6)
  2. Mascheretti S, Hampe J, Kühbacher T, Herfarth H, Krawczak M, Fölsch UR, Schreiber S. Pharmacogenetic Investigation of Response to anti-TNF-a (Infliximab) in Therapy Refractory Crohn’s disease. Pharmacogenomics J 2002; 2: 127-135, (IF 3,2)
  3. Frenzel H, Hampe J, Huse K, Mascheretti SM, Croucher PJP, Lynch NJ, Siebert R, Platzer M, Schreiber S. Mutation detection and physical mapping of the CD11 gene cluster in association with inflammatory bowel disease. Immunogenetics 2002; 53(10):835-42, (IF 2,2)
  4. Lantermann A, Hampe J, Kim WH, Winter TA, Kidd M, Nagy M, R. FU, Schreiber S. Investigation of HLA-DPA1 genotypes as predictors of Inflammatory Bowel Disease in the German, South African and South Korean populations. Int J Colorectal Dis. 2002;17(4):238-44, (IF 2,4), (IF 2,4)
  5. Schreiber S, Hampe J, Nikolaus S, Groessner B, Rosenstiel P, Schottelius A, Kühbacher T, Hämling J, Fölsch UR, Seegert D. Activation of signal transducer and activator of transcription (STAT) 1 in human chronic inflammatory bowel disease. Gut 2002; 71: 379-385, (IF 14,6)
  6. Fisher SA, Hampe J, Macpherson AJS, Forbes A, Lennard-Jones JE, Schreiber S, Curran ME, Mathew CG, Lewis CM. Inflammatory Bowel Disease families show male-specific linkage to IBD3 in the HLA Region. Eur J Hum Genet 2002: 10: 259-265, (IF 4,3)
  7. Tümer Z, Croucher PJP, Jensen LR, Hampe J, Hansen C, Kalscheuer V, Ropers HH, Tommerup N, Schreiber S. Genomic structure, chromosome mapping and expression analysis of the human AVIL gene, and its exclusion as a candidate for IBD2. Gene 2002: 288; 179-185, (IF 2,1)
  8. Cuthbert AP, Fisher SA, Mirza MM, King K, Hampe J, Croucher PJP, Mascheretti S, Sanderson J, Forbes A, Mansfield J, Schreiber S, Lewis CM, Mathew CG. The Contribution of NOD2 Gene Mutations to the Risk and Site of Disease in Inflammatory Bowel Disease. Gastroenterology 2002: 122; 867-874, (IF 16,7)
  9. Hampe J, Grebe J, Nikolaus S, Solberg C, Croucher PJP, Mascheretti S, Jahnsen J, Moum B, Klump B, Krawczak M, Mirza MM, Fölsch UR, Vatn M, Schreiber S. NOD2 genotype and clinical course of Crohn’s disease. Lancet 2002: 359; 1661-1665, (IF 45,2)
  10. Mascheretti S, Hampe J, Croucher PJP, Nikolaus S, Andus T, Schubert S, Olson A, Bao W, Fölsch UR, Schreiber S. Response to infliximab treatment in Crohn's disease is not associated with mutations in the CARD15 (NOD2) gene: An analysis in 534 patients from a two multicenter, prospective GCP-level trials. Pharmacogenetics 2002 Oct;12(7):509-15, (IF 3,4)

2001

  1. Hampe J, Lynch NJ, Daniels S, Bridger S, Macpherson AJS, Stokkers P, Forbes A, Lennard-Jones JE, Mathew CG, Curran ME, Schreiber S. Fine mapping of the chromosome 3p susceptibility locus in Inflammatory Bowel Disease. Gut. 2001 Feb;48(2):191-7, (IF 14,6)
  2. Kühbacher T, Gionchetti P, Hampe J, Helwig U, Rosenstiel P, Campieri M, Buhr HJ, Schreiber S. Activation of signal-transducer and activator of transcription 1 (STAT1) in pouchitis. Clin Exp Immunol. 2001 Mar;123(3):395-401, (IF 3,0)
  3. Hampe J, Wollstein A, Lu T, Frevel HJ, Will M, Manaster C, Schreiber S. An integrated system for high throughput TAQMAN based SNP genotyping. Bioinformatics 2001; 17(7):654-5, (IF 4,9)
  4. Hampe J, Cuthbert A, Croucher PJP, Mirza MM, Mascheretti S, Fisher S, Frenzel H, King K, Hasselmeyer A, MacPherson AJS, Bridger S, van Deventer S, Forbes A, Nikolaus S, Lennard-Jones JE, Foelsch UR, Krawczak M, Lewis C, Schreiber S, Mathew CG. An insertion mutation in the NOD2 gene predisposes to Crohn’s Disease in the German and British populations. Lancet 2001; 357: 1925-1928, (IF 45,2)

Until 2000

  1. Hampe J, Nürnberg P, Epplen C, Jahn S, Grunow R, Epplen JT. Oligonucleotide Fingerprinting as a means to identify and survey long term cultured B cell hybridomas and T cell lines. Hum Antibod Hybridomas 1992;3:186-190, (IF 0,0)
  2. Krawczak M, Böhm I, Nürnberg P, Hampe J, Hundrieser J, Pöche H, Peters C, Slomski R, Kwiatkowska J, Nagy M, Pöpper a, Epplen JT, Schmidtke J. Paternity testing with oligo-nucleotide mulilocus probe (CAC)5/(GTG)5: A multicenter study. Forensic Science Intern 1993;59: 101-117, (IF 2,1)
  3. Nürnberg P, Marczinek K, Thiel G, Hampe J. Parallel genome analysis by one- and two-dimensional DNA fingerprinting in human gliomas. Electrophoresis 1995, 16: 1715-25, (IF 3,0)
  4. Hampe J, Marczinek K, Preuss A, Nürnberg P. Marker Pattern instabilities as a major cause of reproducability problems in 2-D DNA fingerprinting. Electrophoresis 1996, 17: 659-66, (IF 3.0)
  5. Meierkord H, Nürnberg P, Mainz A, Marczinek K, Mrug M, Hampe J. 'Complicated' Autosomal Dominant Familial Spastic Paraplegia is Genetically Distinct from 'Pure' Forms. Arch Neurol 1997, 54: 379-384, (IF 7,4)
  6. Marczinek K, Sugiyama A, Hampe J, Thiel G, Lehmann K, Neumann R, de Leeuw WJF and Nürnberg P. Cloning of minisatellite containing sequences from two-dimensional DNA fingerprinting gels reveals the identity of genomic alterations in low grade gliomas of different patients. Electrophoresis 1997, 18: 1586-1591, (IF 3,0)
  7. Nürnberg P, Tinschert S, Mrug M, Hampe J, Müller CR, Fuhrmann E, Braun HS, Reis A. The Gene for Autosomal Dominant Craniometaphyseal Dysplasia (CMD) Maps to Chromosome 5p and is distinct from the Growth Hormone Receptor Gene. Am J Hum Genet 1997, 61:918-23, (IF 10,9)
  8. Marczinek C, Hampe J, Preuss A, Thiel G, Nürnberg P. Characteristic genomic changes identified in low grade gliomas by 2D DNA fingerprinting. Glia 1998, 23: 130-8, (IF 6,0)
  9. Hampe J, Schreiber S, Wienker T, Nürnberg P. POPSIM: a general population simulation program. Bioinformatics 1998, 14(5), 458-464, (IF 4,9)
  10. Hampe J, Mrowka R, Marczinek K, Nürnberg P. A novel standardization method for two-dimensional DNA fingerprints. Electrophoresis 1998, 18(15): 2874-2879, (IF 3,0)
  11. Schreiber S, Nikolaus S, Hampe J. Activation of nuclear factor kB in inflammatory bowel disease. Gut 1998, 42: 477-484, (IF 14,6)
  12. Curran ME, Lau KF, Hampe J, Bridger S, Macpherson AJS, Cardon LR, Sakul H, Harris TJR, Stokkers P, van Deventer SJH, Mirza M, Raedler A, Kruis W, Meckler U, Theuer D, Herrmann T, Gionchetti P, Lee J, Mathew C, Schreiber S, Lennard-Jones J. Genetic Analysis of Inflammatory Bowel Disease in a Large European Cohort Supports Linkage to Chromosomes 12 and 16. Gastroenterology 1998, 115(5): 1066-71, (IF 16,7)
  13. Hampe J, Hermann B, Bridger S, MacPherson AJ, Mathew CG, Schreiber S. The interferon-gamma gene as a positional and functional candidate gene for inflammatory bowel disease. Int J Colorectal Dis 1998, 13(5-6):260-3, (IF 2,4)
  14. Schreiber S, Nikolaus S, Hampe J, Hämling J, Koop I, Lochs H, Raedler A. Tumour Necrosis Factor-a and interleukin 1b in relapse of Crohn’s Disease. Lancet 1999,353:459-461, (IF 45,2)
  15. Hampe J, Schreiber S, Shaw SH, Lau KF, Bridger S, Macpherson AJS, Cardon LR, Sakul H, Harris TJR, Buckler A, Hall J, Stokkers P, van Deventer SJH, Nürnberg P, Mirza M, Lee J, Lennard-Jones J, Mathew CG, Curran ME. A genome wide scan provides evidence for novel linkages in Inflammatory Bowel Disease in a large European cohort. Am J Hum Genet 1999, 64(3): 808-816, (IF 10,9)
  16. Uhlmann K, Marczinek K, Hampe J, Thiel G, Nürnberg P. Changes in methylation patterns identified by two-dimensional DNA fingerprinting. Electrophoresis 1999, 20(8):1748-55, (IF 3,0)
  17. Hampe J, Shaw SH, Saiz R, Leysens N, Lantermann A, Mascheretti S, Lynch NJ, MacPherson AJS, Bridger S, van Deventer S, Stokkers P, Morin P, Mirza MM, Forbes A, Lennard-Jones JE, Mathew CG, Mark Curran ME, Schreiber S. Linkage of Inflammatory Bowel Disease to Human Chromosome 6p. Am J Hum Genet 1999: 65(6):1647-55, (IF 10,9)
  18. Hampe J, Wienker T, Nürnberg P, Schreiber S. Mapping Genes for Polygenic Disorders: Considerations for Study Design in the Complex Trait of Inflammatory Bowel Disease. Hum Hered 2000, 50:91-101, (IF 1,4)
  19. Olavesen MG, Hampe J, Mirza MM, Saiz R, Lewis CM, Bridger S, Teare D, Easton DF, Herrmann T, Scott G, Hirst J, Sanderson J, Hodgson SV, Lee J, MacPherson AJS, Schreiber S, Lennard-Jones JE, Curran ME, Mathew CG. Analysis of single nucleotide polymorphisms in the interleukin 4 receptor gene for association with inflammatory bowel disease. Immunogenetics 2000, 51:1-7, (IF 2,2)
  20. Hampe J, Heymann K, Kruis W, Raedler A, Fölsch UR, Schreiber S. Anticipation in Inflammatory Bowel Disease: a Phenomenon Caused by an Accumulation of Confounders. Am J Med GenetA 2000, 92(3):178-83, (2,1)